Quantitative Analysis in Nuclear Medicine Imaging / edited by Habib Zaidi.

Springer eBooks

Overview of Nuclear Medical Imaging: Physics and Instrumentation -- Dual-Modality Imaging: More Than the Sum of its Components -- Analytic Image Reconstruction Methods in Emission Computed Tomography -- Iterative Reconstruction Methods -- Collimator-Detector Response Compensation in SPECT -- Attenuation Correction Strategies in Emission Tomography -- Scatter Correction Strategies in Emission Tomography -- Correction for Partial Volume Effects in Emission Tomography -- Image Registration Techniques in Nuclear Medicine Imaging -- Image Segmentation Techniques in Nuclear Medicine Imaging -- Monte Carlo Modeling in Nuclear Medicine Imaging -- Tracer Kinetic Modeling in Nuclear Medicine: Theory and Applications -- Methods for Planar Image Quantification -- Quantitative Analysis in Functional Brain Imaging -- Quantitative Analysis in Myocardial SPECT Imaging -- Quantitative Analysis in Nuclear Oncologic Imaging -- Quantitative Imaging-Based Dosimetry and Treatment Planning in Radionuclide Therapy -- Summary.

This book provides a review of image analysis techniques as they are applied in the field of diagnostic and therapeutic nuclear medicine. Driven in part by the remarkable increase in computing power and its ready and inexpensive availability, this is a relatively new yet rapidly expanding field. Likewise, although the use of radionuclides for diagnosis and therapy has origins dating back almost to the discovery of natural radioactivity itself, radionuclide therapy and, in particular, targeted radionuclide therapy has only recently emerged as a promising approach for therapy of cancer and, to a lesser extent, other diseases. As effort has, therefore, been made to place the reviews provided in this book in a broader context. The effort to do this is reflected by the inclusion of introductory chapters that address basic principles of nuclear medicine imaging, followed by overview of issues that are closely related to quantitative nuclear imaging and its potential role in diagnostic and therapeutic applications. The different chapters discuss the basic principles and various steps required for obtaining quantitatively accurate data from nuclear medicine images including data collection methods and algorithms used to correct them for physical degrading factors (e.g. collimator response, attenuation, scatter, partial volume effect), and image reconstruction algorithms (analytic, iterative) as well as image processing and analysis techniques as their clinical and research applications in neurology, cardiology and oncology. Some algorithms are described and illustrated with some useful features and clinical applications. Other potential applications of quantitative image analysis such as image-guided radiation therapy are also discussed.

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