Regional Cancer Therapy / edited by Peter M. Schlag, Ulrike Stein, Alexander M. M. Eggermont.

Springer eBooks

Background -- Biological Background -- Pharmacological Background -- Isolated Limb and Organ Perfusion Laboratory Models -- Techniques and Prerequisites for Regional Therapy -- Interventional Radiotherapy -- Surgical Strategies -- Regional Thermotherapy -- Radiofrequency Thermal Ablation -- Cryoablation for Primary and Secondary Liver Tumors -- A Personal History of Photodynamic Therapy -- Ultrasound-Guided Therapy -- Nanocarriers and Drug Delivery -- Local Gene Therapy for Cancer -- Indications and Results for Different Tumor Entities -- Regional Chemotherapy of Primary and Metastatic Liver Tumors -- Focal Liver Ablation Techniques in Primary and Secondary Liver Tumors -- Regional Therapy for Peritoneal Surface Malignancy -- Malignant Peritoneal Mesothelioma -- Regional Therapy of Pancreatic Cancer -- Regional Breast Cancer Treatment -- Regional Therapy in Ovarian Cancer -- Regional Therapy of Bladder Tumors -- Regional Therapy of Rectal Cancer -- Percutaneous Laser Ablation of Lung Metastases -- Regional Therapy of Brain Tumors -- Hyperthermic Intrapleural Chemotherapy in Pleural Malignancy -- Isolated Limb Perfusion in Advanced Soft Tissue Sarcomas -- Isolated Limb Perfusion for Melanoma in Transit Metastases -- Outpatient Brachytherapy with Seeds.

This volume provides a biological and pharmacological background for regional cancer therapy, strategies and techniques for regional therapies, and specific indications and results for different tumor entities. Clinical trial concepts and detailed treatment protocols are also presented. Part I describes biological and pharmacological fundamentals for therapy and introduces laboratory models for isolated limb and organ perfusion. Topics introduced in Part II include interventional radiotherapy, surgical strategies, regional thermotherapy, radiofrequency thermal ablation, cryoablation, nanocarriers and drug delivery, and local gene therapy for cancer. Highlights of Part III include regional chemotherapy of primary and metastatic liver tumors and focal liver ablation techniques in primary and secondary liver tumors. Regional Cancer Therapy is essential reading for researchers and clinicians engaged in seeking advanced therapeutic options for cancer patients worldwide.

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