Biological basis of alcohol-induced cancer / edited by Vasilis Vasiliou, Samir Zakhari, Helmut K. Seitz, Jan B. Hoek.

Springer eBooks

Introduction -- Alcohol and breast cancer: Reconciling epidemiological and molecular data -- Genetic-epidemiological evidence for the role of acetaldehyde in cancers related to alcohol drinking -- Alcohol and Cancer: an Overview With special Emphasis on the Role of Acetaldehyde and Cytochrome P-4502E1 -- Implications of acetaldehyde-derived DNA adducts for understanding alcohol related carcinogenesis -- The role of iron in alcohol-mediated hepatocarcinogenesis -- Alcoholic Cirrhosis and Hepatocellular Carcinoma -- TLR4-dependent tumor-initiating stem cell-like cells (TICs) in alcohol-associated hepatocellular carcinogenesis -- Synergistic Toxic Interactions Between CYP2E1, LPS/TNF? and JNK/p38 MAP Kinase and their Implications in Alcohol-induced Liver Injury -- Understanding the tumor suppressor PTEN in chronic alcoholism and hepatocellular carcinoma -- Alcohol consumption, Wnt/b-catenin signaling and hepatocarcinogensis -- Alcohol and HCV: Implications for Liver Cancer -- Application of Mass Spectrometry-based Metabolomics in Identification of Early Noninvasive Biomarkers of Alcohol-Induced Liver Disease Using Mouse Model -- Alcohol Metabolism by Oral Streptococci and Interaction with Human Papillomavirus Leads to Malignant Transformation of Oral Keratinocytes -- Genetic polymorphisms of alcohol dehydrogense-1B and aldehyde dehydrogenase-2, alcohol flushing, mean corpuscular volume, and aerodigestive tract neoplasia in Japanese drinkers -- Acetaldehyde and Retinaldehyde-Metabolizing Enzymes in Colon and Pancreatic cancers -- Alcohol, Carcinoembryonic Antigen Processing and Colorectal Liver Metastases -- Alcohol Consumption and Antitumor Immunity: Dynamic Changes from Activation to Accelerated Deterioration of the Immune System -- A Perspective on Chemoprevention by Resveratrol in Head and Neck Squamous Cell Carcinoma -- The effects of alcohol and aldehyde dehydrogenases on disorders of hematopoiesis -- The effect of alcohol on sirt1 expression and function in animal and human models of hepatocellular carcinoma (HCC) -- Transgenic Mouse Models for Alcohol Metabolism, Toxicity and Cancer -- Fetal alcohol exposure increases susceptibility to carcinogenesis and promotes tumor progression in prostate gland -- Fetal Alcohol Exposure and Mammary Tumorigenesis in Offspring: Role of the Estrogen and Insulin-like Growth Factor Systems.

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