The neuropathology of huntington’s disease: classical findings, recent developments and correlation to functional neuroanatomy / Udo Rüb, Jean Paul G. Vonsattel, Helmut Heinsen, Horst-Werner Korf.
Tipo de material:
TextoSeries Advances in Anatomy, Embryology and Cell Biology ; 217Editor: Cham : Springer International Publishing : Springer, 2015Edición: 1st ed. 2015Descripción: xiv, 146 páginas : 50 ilustraciones, 47 ilustraciones en colorTipo de contenido: - texto
- computadora
- recurso en línea
- 9783319192857
- RC321-580
Springer eBooks
1. Introduction -- 2. The neuropathological grading of Huntington disease -- 3. The cerebral cortex in Huntington´s disease -- 4. Degeneration of select motor and limbic nuclei of the thalamus in Huntington’s disease -- 5. Consistent and widespread degeneration of the cerebellum in Huntington’s disease -- 6. Elucidation of the role of the premotor oculomotor brainstem nuclei in the pathogenesis of oculomotor dysfunctions in Huntington’s disease -- 7. Widespread brainstem neurodegeneration in Huntington’s disease -- 8. Intraneuronal transport and defense mechanisms with possible pathogenetic relevance in Huntington’s disease -- 9. The disease protein huntingtin and neuronal protein aggregations in Huntington’s disease -- 10. Pathological nerve cell alterations in Huntington’s disease (HD) and their possible role for the demise of nerve cells -- 11. Conclusions and outlook.
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