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Macpf/cdc proteins - agents of defence, attack and invasion / edited by Gregor Anderluh, Robert Gilbert.

Colaborador(es): Tipo de material: TextoTextoSeries Subcellular Biochemistry ; 80Editor: Dordrecht : Springer Netherlands : Springer, 2014Descripción: xi, 329 páginas : 57 ilustraciones, 52 ilustraciones en colorTipo de contenido:
  • texto
Tipo de medio:
  • computadora
Tipo de portador:
  • recurso en línea
ISBN:
  • 9789401788816
Formatos físicos adicionales: Edición impresa:: Sin títuloClasificación LoC:
  • R-RZ
Recursos en línea:
Contenidos:
Part I: Overview of MACPF/CDCs -- Introduction: Brief Historical Overview -- Distribution of MACPF/CDC proteins -- Evolution of the Complement System -- Part II: Structures of MACPF/CDCs -- Structural Features of Cholesterol Dependent Cytolysins and Comparison to other MACPF-domain containing proteins -- Perfringolysin O Structure and Mechanism of Pore Formation as a Paradigm for Cholesterol-Dependent Cytolysins -- Structural Biology of the Membrane Attack Complex -- Part III: Functional aspect --  Membrane Interactions and Cellular Effects of MACPF/CDC Proteins -- The Biology of Pneumolysin -- Multifaceted Activity of Listeriolysin O, the Cholesterol-Dependent Cytolysin of Listeria monocytogenes -- Perforin - a Key Pore-Forming Protein for Immune Control of Viruses and Cancer -- Perforin and Human Diseases -- The role of MACPF Proteins in the Biology of Malaria and other Apicomplexan Parasites -- Chlamydial MACPF Protein CT153 -- Fungal MACPF-Like Proteins and Aegerolysins: Bi-Component Pore-Forming Proteins? -- Fluorescence Imaging of MACPF/CDC Proteins: New Techniques and Their Application.
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Springer eBooks

Part I: Overview of MACPF/CDCs -- Introduction: Brief Historical Overview -- Distribution of MACPF/CDC proteins -- Evolution of the Complement System -- Part II: Structures of MACPF/CDCs -- Structural Features of Cholesterol Dependent Cytolysins and Comparison to other MACPF-domain containing proteins -- Perfringolysin O Structure and Mechanism of Pore Formation as a Paradigm for Cholesterol-Dependent Cytolysins -- Structural Biology of the Membrane Attack Complex -- Part III: Functional aspect --  Membrane Interactions and Cellular Effects of MACPF/CDC Proteins -- The Biology of Pneumolysin -- Multifaceted Activity of Listeriolysin O, the Cholesterol-Dependent Cytolysin of Listeria monocytogenes -- Perforin - a Key Pore-Forming Protein for Immune Control of Viruses and Cancer -- Perforin and Human Diseases -- The role of MACPF Proteins in the Biology of Malaria and other Apicomplexan Parasites -- Chlamydial MACPF Protein CT153 -- Fungal MACPF-Like Proteins and Aegerolysins: Bi-Component Pore-Forming Proteins? -- Fluorescence Imaging of MACPF/CDC Proteins: New Techniques and Their Application.

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