Epigenetics and Chromatin /
edited by Philippe Jeanteur.
- xiii, 266 páginas recurso en línea.
- Progress in Molecular and Subcellular Biology, 38 0079-6484 ; .
Springer eBooks
Chromatin Remodeling Factors and DNA Replication -- Epigenetic Inheritance of Chromatin States Mediated by Polycomb and Trithorax Group Proteins in Drosophila -- How to Pack the Genome for a Safe Trip -- Chromatin Modifications on the Inactive X Chromosome -- Chromatin Mechanisms in Drosophila Dosage Compensation -- DNA Methylation in Epigenetic Control of Gene Expression -- The Epigenetic Breakdown of Cancer Cells: From DNA Methylation to Histone Modifications -- Developmental Regulation of the ?-Globin Gene Locus -- Epigenetic Regulation of Mammalian Imprinted Genes: From Primary to Functional Imprints -- Seed Development and Genomic Imprinting in Plants.
Epigenetics refers to heritable patterns of gene expression which do not depend on alterations of genomic DNA sequence. This book provides a state-of-the-art account of a few selected hot spots by scientists at the edge in this extremely active field. It puts special emphasis on two main streams of research. One is the role of post-translational modifications of proteins, mostly histones, on chromatin structure and accessibility. The other one deals with parental genomic imprinting, a process which allows to express a few selected genes from only one of the parental allele while extinguishing the other.