Introduction -- Part I: Information -- The Nature of Information -- The Transmission of Information -- Sets and Combinatorics -- Probability and Likelihood -- Randomness and Complexity -- Systems, Networks and Circuits -- Algorithms -- Part II: Biology -- Introduction to Part II -- The Nature of Living Things -- The Molecules of Life -- Part III: Applications -- Introduction to Part III -- Genomics -- Proteomics -- The Glycome, Lipidome and Microbiome -- Interactomics -- The Nervous System -- Metabolomics and Metabonomics -- Phenomics -- Medical Applications -- Ecosystems Management -- The Organization of Knowledge.