Mtor inhibition for cancer therapy: past, present and future / 
edited by Monica Mita, Alain Mita, Eric K. Rowinsky. 
 - 1st ed. 2016. 
 - vi, 300 páginas :  16 ilustraciones, 13 ilustraciones en color. 
<br/><br/> Springer eBooks 
<br/><br/>Forward -- Past -- mTOR inhibitors: a little bit of history -- Present -- The mTOR pathway  -- The evolving role of mTOR inhibitors in renal cell carcinoma -- The role of mTOR inhibitors in breast cancer -- The role of mTOR inhibitors in neuroendocrine tumors -- New indications of mTOR inhibitors in rare tumors -- The role of mTOR inhibitors in the treatment of hematological malignancies -- The clinical pharmacology and toxicity profile of rapalogs -- Resistance to mTOR inhibitors -- Rational combinations of mTOR inhibitors as anticancer strategies -- Future -- Predictive biomarkers of response to mTOR inhibitors -- The potential future indication of rapamycin analogs for the treatment of other solid tumors -- mTOR inhibition beyond rapalogs -- mTOR, aging and cancer: the missing link? -- New study design for mTOR inhibitors and other biological agents -- Future directions for the development of mTOR inhibitors. 
<br/><br/><label>ISBN: </label>9782817804927 
<br/><br/><label>LC Class. No.: </label>RC254-282