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Studies on experimental toxicology and pharmacology / edited by Stephen M. Roberts, James P. Kehrer, Lars-Oliver Klotz.

Colaborador(es): Tipo de material: TextoTextoSeries Oxidative Stress in Applied Basic Research and Clinical PracticeEditor: Cham : Springer International Publishing : Imprint: Humana Press, 2015Edición: 1st ed. 2015Descripción: xvi, 498 páginas : 96 ilustraciones, 53 ilustraciones en colorTipo de contenido:
  • texto
Tipo de medio:
  • computadora
Tipo de portador:
  • recurso en línea
ISBN:
  • 9783319190969
Formatos físicos adicionales: Edición impresa:: Sin títuloClasificación LoC:
  • QH573-671
Recursos en línea:
Contenidos:
Part I. Toxicological Mechanisms and Evaluation of Oxidative Stress -- A historical perspective on oxidative stress and intracellular redox control -- An overview of free radicals as causes and consequences of toxicity -- Oxidants, radicals, free radicals, and other bad stuff in mechanisms of toxicity -- Lipid oxidation -- Protein oxidation and toxicology -- Oxidative stress and DNA damage association with carcinogenesis: A truth or a myth? -- Glutathione and thiols -- Reactive oxygen species as initiators and mediators of cellular signaling processes -- Role of oxidative stress in the process of carcinogenesis -- Part II. Agents that produce toxicity – mechanisms and therapeutic interventions -- Isolation of murine adult bone marrow and fetal liver cells for mechanistic assessment of hematotoxicity caused by organic solvents -- Oxidative stress and ethanol toxicity -- Pharmaceutical agents -- Insecticides and herbicides -- Health effects of indoor air pollution due to cooking with biomass fuel -- Outdoor pollutants -- Oxidative Stress and the Inorganic Carcinogens -- UV-induced signaling: Role of reactive oxygen species -- Nanomaterials -- Chemical warfare agents -- Part III. Special topics -- On the biochemistry of antioxidants — current aspects.-Prevention of age-related diseases — Effects of antioxidant supplements -- The neural progenitor cell (NPC) niche in the adult brain provides a target for neurotoxicity — a potential Adverse Outcome Pathway for ROS-induced NPC dysfunction with higher sensitivity during aging. -- Oxygen toxicity: From cough to convulsion -- Oxidative stress in reproductive toxicology -- Toxicogenomics-based assessment of xenobiotic-induced oxidative stress -- Aquatic and marine biology.
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Springer eBooks

Part I. Toxicological Mechanisms and Evaluation of Oxidative Stress -- A historical perspective on oxidative stress and intracellular redox control -- An overview of free radicals as causes and consequences of toxicity -- Oxidants, radicals, free radicals, and other bad stuff in mechanisms of toxicity -- Lipid oxidation -- Protein oxidation and toxicology -- Oxidative stress and DNA damage association with carcinogenesis: A truth or a myth? -- Glutathione and thiols -- Reactive oxygen species as initiators and mediators of cellular signaling processes -- Role of oxidative stress in the process of carcinogenesis -- Part II. Agents that produce toxicity – mechanisms and therapeutic interventions -- Isolation of murine adult bone marrow and fetal liver cells for mechanistic assessment of hematotoxicity caused by organic solvents -- Oxidative stress and ethanol toxicity -- Pharmaceutical agents -- Insecticides and herbicides -- Health effects of indoor air pollution due to cooking with biomass fuel -- Outdoor pollutants -- Oxidative Stress and the Inorganic Carcinogens -- UV-induced signaling: Role of reactive oxygen species -- Nanomaterials -- Chemical warfare agents -- Part III. Special topics -- On the biochemistry of antioxidants — current aspects.-Prevention of age-related diseases — Effects of antioxidant supplements -- The neural progenitor cell (NPC) niche in the adult brain provides a target for neurotoxicity — a potential Adverse Outcome Pathway for ROS-induced NPC dysfunction with higher sensitivity during aging. -- Oxygen toxicity: From cough to convulsion -- Oxidative stress in reproductive toxicology -- Toxicogenomics-based assessment of xenobiotic-induced oxidative stress -- Aquatic and marine biology.

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