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001			278181
003			MX-SnUAN
005			20170705134200.0
007			cr nn 008mamaa
008			150903s2006 xxu| o |||| 0|eng d
020			_a9780387329567 _99780387329567
024	7		_a10.1007/0387329560 _2doi
035			_avtls000331014
039		9	_a201509030727 _bVLOAD _c201404120558 _dVLOAD _c201404090338 _dVLOAD _c201401311359 _dstaff _y201401301159 _zstaff
040			_aMX-SnUAN _bspa _cMX-SnUAN _erda
050		4	_aRB155-155.8
100	1		_aJanson, Christopher G. _eautor _9301599
245	1	0	_aPeptide Nucleic Acids, Morpholinos and Related Antisense Biomolecules / _cby Christopher G. Janson, Matthew J. During.
264		1	_aBoston, MA : _bSpringer US, _c2006.
300			_axviii, 274 páginas, _brecurso en línea.
336			_atexto _btxt _2rdacontent
337			_acomputadora _bc _2rdamedia
338			_arecurso en línea _bcr _2rdacarrier
347			_aarchivo de texto _bPDF _2rda
490	0		_aMedical Intelligence Unit
500			_aSpringer eBooks
505	0		_aResearch Applications -- The Many Faces of PNA -- Modulation of Nucleic Acid Information Processing by PNAs -- Targeted Gene Delivery -- Imaging Gene Expression in the Brain with Peptide Nucleic Acid (PNA) Antisense Radiopharmaceuticals and Drug Targeting Technology -- Receptor-Specific Targeting with Complementary Peptide Nucleic Acids Conjugated to Peptide Analogs and Radionuclides -- Morpholinos and PNAs Compared -- Chemistry of Locked Nucleic Acids (LNA) -- Recent Applications of RNA Interference (RNAi) in Mammalian Systems -- Clinical Applications -- Peptide Nucleic Acids as Epigenetic Inhibitors of HIV-1 -- Therapeutic Uses of Peptide Nucleic Acids (PNA) in Oncology -- PNAs as Novel Cancer Therapeutics -- Medicinal Chemistry of Plasmid DNA with Peptide Nucleic Acids -- Locked Nucleic Acids (LNA) and Medical Applications -- Peptide Nucleic Acids as Agents to Modify Target Gene Expression and Function -- Peptide Nucleic Acids -- The Use of PNAs and Their Derivatives in Mitochondrial Gene Therapy -- Gene Silencing through RNA Interference -- Transcriptional Activation of Human CREB Gene Promoter Using Bis-PNA (Peptide Nucleic Acid).
520			_aThis volume is unique to the existing literature in the Peptide Nucleic Acid field, in that it focuses on comparing and contrasting PNA with other available oligonucleotide homologues and considers areas in which these biomolecules could be profitably applied to clinical and diagnostic applications. Part I of the book addresses comparative strengths and weaknesses of various nucleoside homologues. Part II of the book addresses specific translational or clinical applications for PNA and related antisense biomolecules. The editors have succeeded in presenting a balanced yet broad view of the methods available for gene targeting and modification.
590			_aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700	1		_aDuring, Matthew J. _eautor _9301600
710	2		_aSpringerLink (Servicio en línea) _9299170
776	0	8	_iEdición impresa: _z9780306482304
856	4	0	_uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/0-387-32956-0 _zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
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999			_c278181 _d278181