000			04862nam a22003975i 4500
001			278233
003			MX-SnUAN
005			20160429153854.0
007			cr nn 008mamaa
008			150903s2006 xxu| o |||| 0|eng d
020			_a9780387338279 _99780387338279
024	7		_a10.1007/0387338276 _2doi
035			_avtls000331105
039		9	_a201509030712 _bVLOAD _c201404120606 _dVLOAD _c201404090347 _dVLOAD _c201401311403 _dstaff _y201401301201 _zstaff
040			_aMX-SnUAN _bspa _cMX-SnUAN _erda
050		4	_aRC261-271
100	1		_aHatfield, Dolph L. _eeditor. _9301702
245	1	0	_aSelenium : _bIts Molecular Biology and Role in Human Health / _cedited by Dolph L. Hatfield, Marla J. Berry, Vadim N. Gladyshev.
250			_aSecond Edition.
264		1	_aBoston, MA : _bSpringer US, _c2006.
300			_axxiv, 420 páginas, _brecurso en línea.
336			_atexto _btxt _2rdacontent
337			_acomputadora _bc _2rdamedia
338			_arecurso en línea _bcr _2rdacarrier
347			_aarchivo de texto _bPDF _2rda
500			_aSpringer eBooks
505	0		_aSelenium: A historical perspective -- Selenium: A historical perspective -- Biosynthesis of selenocysteine and its incorporation into protein -- Selenium metabolism in prokaryotes -- Mammalian and other eukaryotic selenocysteine tRNAs -- Evolution of selenocysteine decoding and the key role of selenophosphate synthetase in the pathway of selenium utilization -- SECIS RNAs and K-turn binding proteins. A survey of evolutionary conserved RNA and protein motifs -- SECIS binding proteins and eukaryotic selenoprotein synthesis -- The importance of subcellular localization of SBP2 and EFsec for selenoprotein synthesis -- Selenocysteine biosynthesis and incorporation may require supramolecular complexes -- Selenium-containing proteins -- Selenoproteins and selenoproteomes -- Deletion of selenoprotein P gene in the mouse -- Selenium and methionine sulfoxide reduction -- Selenoprotein W in development and oxidative stress -- The 15-kDa selenoprotein (Sep15): functional analysis and role in cancer -- Regulation of glutathione peroxidase-1 expression -- Selenoproteins of the glutathione system -- New roles of glutathione peroxidase-1 in oxidative stress and diabetes -- Selenoproteins of the thioredoxin system -- Mitochondrial and cytosolic thioredoxin reductase knockout mice -- Selenium, deiodinases and endocrine function -- Biotechnology of selenocysteine -- Selenium and human health -- Selenium, selenoproteins and brain function -- Selenium as a cancer preventive agent -- Peering down the kaleidoscope of thiol proteomics and unfolded protein response in studying the anticancer action of selenium -- Genetic variation among selenoprotein genes and cancer -- Selenium and viral infections -- Role of selenium in HIV/AIDS -- Effects of selenium on immunity and aging -- Selenium and male reproduction -- Mouse models for assessing the role of selenoproteins in health and development -- Drosophila as a tool for studying selenium metabolism and role of selenoproteins -- Selenoproteins in parasites -- Incorporating ‘omics’ approaches to elucidate the role of selenium and selenoproteins in cancer prevention -- Selenium-induced apoptosis -- Selenoprotein mimics -- Update of human dietary standards for selenium.
520			_aSelenium is an essential trace element in the diet of humans and many other life forms. As discussed in this book, selenium plays an important role in preventing certain forms of cancer, heart disease and other cardiovascular and muscle disorders. Evidence points to numerous other health benefits including an indispensable function in development, male reproduction and the immune system. In addition, selenium serves as an antiviral agent and may delay the onset of AIDS in HIV positive patients and delay the aging process. This element occurs primarily in cellular proteins in the form of a novel amino acid selenocysteine. Selenocysteine is the 21st amino acid in the genetic code and is cotranslationally incorporated into protein in response to the codon, UGA. Selenoproteins control redox homeostasis and are involved in variety of cellular pathways. The emphasis of this book is on the current status of the molecular biology of selenium. The importance of this element in human health is also highlighted.
590			_aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700	1		_aBerry, Marla J. _eeditor. _9301703
700	1		_aGladyshev, Vadim N. _eeditor. _9301704
710	2		_aSpringerLink (Servicio en línea) _9299170
776	0	8	_iEdición impresa: _z9780387338262
856	4	0	_uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/0-387-33827-6 _zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
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999			_c278233 _d278233