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008			150903s2005 xxu| o |||| 0|eng d
020			_a9780387291482 _99780387291482
024	7		_a10.1007/0387291482 _2doi
035			_avtls000330703
039		9	_a201509030724 _bVLOAD _c201404120520 _dVLOAD _c201404090301 _dVLOAD _c201401311348 _dstaff _y201401301152 _zstaff
040			_aMX-SnUAN _bspa _cMX-SnUAN _erda
050		4	_aQH345
100	1		_aOhyama, Takashi. _eautor _9301796
245	1	0	_aDNA Conformation and Transcription / _cby Takashi Ohyama.
264		1	_aBoston, MA : _bSpringer US, _c2005.
300			_axii, 211 páginas, _brecurso en línea.
336			_atexto _btxt _2rdacontent
337			_acomputadora _bc _2rdamedia
338			_arecurso en línea _bcr _2rdacarrier
347			_aarchivo de texto _bPDF _2rda
490	0		_aMolecular Biology Intelligence Unit
500			_aSpringer eBooks
505	0		_aMultifarious DNA Structures Found In Genomes -- DNA -- Sequence-Dependent Variability of B-DNA -- Intrinsic DNA Curvature and Transcription -- Curved DNA and Prokaryotic Promoters -- Repression of Transcription by Curved DNA and Nucleoid Protein H-NS -- Curved DNA and Transcription in Eukaryotes -- Putative Roles of kin17, a Mammalian Protein Binding Curved DNA, in Transcription -- Implied Roles of Left-Handed Z-DNA, Triplex DNA, DNA Supercoiling, and Miscellaneous Alternative Conformations of DNA in Transcription -- Roles for Z-DNA and Double-Stranded RNA in Transcription -- Do DNA Triple Helices or Quadruplexes Have a Role in Transcription? -- Nucleic Acid Structures and the Transcription Defects in Fragile X Syndrome and Friedreich’s Ataxia -- Possible Roles of DNA Supercoiling in Transcription -- DNA-Bending Proteins: Architectural Regulation of Transcription -- Gene Regulation by HMGA and HMGB Chromosomal Proteins and Related Architectural DNA-Binding Proteins -- Molecular Mechanisms of Male Sex Determination -- Chromatin Infrastructure in Transcription: Roles of DNA Conformation and Properties -- The Role of Unusual DNA Structures in Chromatin Organization for Transcription -- DNA Bendability and Nucleosome Positioning in Transcriptional Regulation.
520			_aDespite remarkable progress in genome science, we are still far from a clear understanding of how genomic DNA is packaged without entanglement into a nucleus, how genes are wrapped up in chromatin, how chromatin structure is faithfully inherited from mother to daughter cells, and how the differential expression of genes is enabled in a given cell type. Exploring and answering these questions constitutes one of the next frontiers in the 21st century. We are just beginning to appreciate how Multifarious DNA structures provide additional structural and functional dimensions to chromatin organization and gene expression. DNA Conformation and Transcription is the first book that compiles the fruits of the studies that have been performed to date to solve the riddle ‘written’ in DNA conformation ("conformation code"). This book provides a comprehensive overview of the field by covering history of the field, up-to-date topics, clarifications of present day research, and future perspective of what is still to be discovered. Thus, it serves as an invaluable source of information on the "conformation code".
590			_aPara consulta fuera de la UANL se requiere clave de acceso remoto.
710	2		_aSpringerLink (Servicio en línea) _9299170
776	0	8	_iEdición impresa: _z9780387255798
856	4	0	_uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/0-387-29148-2 _zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
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999			_c278284 _d278284