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001 278476
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020 _a9780387286723
_9978-0-387-28672-3
024 7 _a10.1007/0387286721
_2doi
035 _avtls000330566
039 9 _a201509030723
_bVLOAD
_c201404120505
_dVLOAD
_c201404090247
_dVLOAD
_c201401311345
_dstaff
_y201401291458
_zstaff
_wmsplit0.mrc
_x986
050 4 _aRB155-155.8
100 1 _aAmendt, Brad A.
_eautor
_9302131
245 1 4 _aThe Molecular Mechanisms of Axenfeld-Rieger Syndrome /
_cby Brad A. Amendt.
264 1 _aBoston, MA :
_bSpringer US,
_c2005.
300 _aX, 106 p.
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aMedical Intelligence Unit
500 _aSpringer eBooks
505 0 _aIdentification of the Gene Involved in 4q25-Linked Axenfeld-Rieger Syndrome, PITX2 -- Winged Helix/Forkhead Transcription Factors and Rieger Syndrome -- Rieger Syndrome and PAX6 Deletion -- The Molecular and Biochemical Basis of Axenfeld-Rieger Syndrome -- Role of PITX2 in the Pituitary Gland -- Expression and Function of Pitx2 in Chick Heart Looping -- The Multiple Roles of Pitx2 in Heart Development -- The Role of PITX2 in Tooth Development -- PITX Genes and Ocular Development -- An Overview of Axenfeld-Rieger Syndrome and the Anterior Segment Developmental Disorders.
520 _aThe Molecular Mechanisms of Axenfeld-Rieger Syndrome describes the current research and clinical findings of the heterogeneous disorder termed Axenfeld-Rieger Syndrome (ARS). The book provides an in-depth analysis of this phenotypic diverse disorder and is designed to detail the current molecular and biochemical research involved in studying genetic defects. This book brings together the complete analysis of a human genetic defect using humans, mouse and chick epigenetic and genetic studies, combined with cell culture and in vitro analyses. It is a comprehensive study of a unique set of genes and their mutant activities. A molecular basis for the genetic and phenotypic anomalies observed in ARS patients is provided, with especially detailed descriptions of eye, tooth, and heart development.
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9780387262222
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/0-387-28672-1
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
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999 _c278476
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