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020 _a9780387272702
_9978-0-387-27270-2
024 7 _a10.1007/b138851
_2doi
035 _avtls000330370
039 9 _a201509031102
_bVLOAD
_c201405070515
_dVLOAD
_c201401311338
_dstaff
_c201401311202
_dstaff
_y201401291453
_zstaff
_wmsplit0.mrc
_x790
050 4 _aQH505
100 1 _aSimon, Matthew.
_eautor
_9302467
245 1 0 _aEmergent Computation :
_bEmphasizing Bioinformatics /
_cby Matthew Simon.
264 1 _aNew York, NY :
_bSpringer New York,
_c2005.
300 _aXIV, 423 páginas, 274 illus.
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aBiological and Medical Physics Biomedical Engineering,
_x1618-7210
500 _aSpringer eBooks
505 0 _aEmergent Computation: Bioinformatics -- A Review of Chemistry -- A Review of Aspects of Automata Theory -- The Beginning Numbers -- Regular Languages: DNA and RNA -- Context-Free Languages: DNA and RNA -- Context-Sensitive Languages: DNA, RNA, Proteins -- Turing Machines and Sub-Turing Machines -- Splicing Systems, H Systems -- tRNA Structure -- Semigroups and Bioinformatics -- Automata Theory and Disciplines Other than Bioinformatics -- Automata Theory: Non-Bioinformatics Emergent Computation.
520 _aEmergent Computation is concerned with recent applications of Mathematical Linguistics or Automata Theory. This subject has a primary focus upon "Bioinformatics" (the Genome and arising interest in the Proteome), but the closing chapter also examines applications in Biology, Medicine, Anthropology, etc. The book is composed of an organized examination of DNA, RNA, and the assembly of amino acids into proteins. Rather than examine these areas from a purely mathematical viewpoint (that excludes much of the biochemical reality), the author uses scientific papers written mostly by biochemists based upon their laboratory observations. Thus while DNA may exist in its double stranded form, triple stranded forms are not excluded. Similarly, while bases exist in Watson-Crick complements, mismatched bases and abasic pairs are not excluded, nor are Hoogsteen bonds. Just as there are four bases naturally found in DNA, the existence of additional bases is not ignored, nor amino acids in addition to the usual complement of 20. Can there be more than "64" possible codons? RNA is examined from the point of view of Nussinov plots. All information is presented from the point of view of regular, context-free, and context sensitive languages, as well as Turing machines and Sequential Machines (and their corresponding semi-groups). Relationships to other subjects of mathematics such as Complex numbers, Quaternions, Algebraic-Topology, and Knot Theory are also mentioned. An examination is made of Splicing Systems as well as Dominoes. Shortcomings illustrating the dangers of mathematical abstractions that ignore biochemistry are pointed out. The papers examine the subjects of interest from the point of view of applying language theory to search for new results, but also as biological-automatons (implementations or machines) to do calculations. This book will be of value to those studying Bioinformatics, Biochemistry, Computer-Science, Mathematical Linguistics, and Biology, as well as Pharmacology (with the possible promise of medically active artificial DNA, RNA, and proteins). Laboratory results to demonstrate the usefulness of the topics discussed are demonstrated both in vitro and in vivo.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9780387220468
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/b138851
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c278683
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