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007			cr nn 008mamaa
008			150903s2010 xxu| o |||| 0|eng d
020			_a9780387774985 _99780387774985
024	7		_a10.1007/9780387774985 _2doi
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040			_aMX-SnUAN _bspa _cMX-SnUAN _erda
050		4	_aRC261-271
100	1		_aNeoptolemos, John P. _eautor _9303744
245	1	0	_aPancreatic Cancer / _cby John P. Neoptolemos, Raul Urrutia, James L. Abbruzzese, Markus W. Büchler.
264		1	_aNew York, NY : _bSpringer New York, _c2010.
300			_axxIx, 1390 páginas 208 ilustraciones, 60 ilustraciones en color. eReference. In 2 volumes, not available separately. _brecurso en línea.
336			_atexto _btxt _2rdacontent
337			_acomputadora _bc _2rdamedia
338			_arecurso en línea _bcr _2rdacarrier
347			_aarchivo de texto _bPDF _2rda
500			_aSpringer eBooks
505	0		_aEpidemiology: world overview, risk factors, prospects for prevention -- Development and structure of pancreas -- Pathologic classification and biological behaviour of pancreatic neoplasia -- Developmental molecular biology of the pancreas -- Molecular pathology of precursor lesions of pancreatic cancer, pancreatic intraepithelial neoplasia (PanIN), intraductal papillary mucinous neoplasm (IPMN), and mucinous cystic neoplasm (MCN) -- Epigenetics: its fundamentals and applications to a revised comprehensive progression model for pancreatic cancer -- Molecular pathology of pancreatic neuroendocrine tumours MEN-1: gastrinomas, insulinoma, Non-Functioning Tumours, VIPoma, glucagonoma, Von Hippel-Lindau, Neurofibromatosis -- Sporadic neuroendocrine pancreatic tumours -- Molecular pathology of non-pancreatic cancer lesions: Ampullary cancer, intra-pancreatic bile duct cancer, and duodenal cancer -- Miscellaneous non-pancreatic non-endocrine tumours -- Novel molecular relationships between chronic pancreatitis and cancer -- Pancreatic cancer stem cells -- Cell cycle control: signalling pathways in pancreatic pathogenesis -- Apoptosis: signalling pathways in pancreatic pathogenesis -- EGFR: signalling pathways in pancreatic pathogenesis Pl3, Akt, lKK, Ras, Raf, MAPKK, ERK -- Hedgehog: signalling pathways in pancreatic pathogenesis -- Smad4/TGF-ß pathway: signalling pathways in pancreatic pathogenesis -- Notch signalling in pancreatic morphogenesis and pancreatic cancer -- Molecular characterization of pancreatic cell lines -- Mouse models of exocrine pancreatic cancer -- Principles and applications of microarray gene expression in pancreatic cancer -- Principles and applications of proteomics in pancreatic cancer -- Tumour-stromal interaction: invasion and metastases -- Genetic susceptibility, high risk groups, chronic and hereditary pancreatitis, familial pancreatic cancer syndromes -- Inherited endocrine pancreatic tumors associated with Multiple Endocrine Neoplasia Type 1 Von-Hippel-Lindau Syndrome, and Neurofibromatosis Type 1 -- Clinical decision making in pancreatic cancer -- Paraneoplastic syndromes -- Diagnostic and therapeutic response markers -- CT and fusion PET-CT Diagnosis, staging, and follow-up -- MRI and MRCP: diagnosis and staging of pancreatic cancer -- EUS Diagnosis and staging -- Laparoscopy and laparoscopic ultrasound: diagnosis and staging -- Overview of palliative management for pancreatic cancer -- Endoscopy -- Interventional radiology -- Role of palliative surgery in advanced pancreatic cancer -- Chemotherapy for advanced pancreatic cancer -- Developments in chemoradiation in advanced pancreatic cancer -- Surgical resection for pancreatic cancer -- Role of venous resection in pancreatic cancer surgery -- Pathological reporting and staging following resection -- Japanese Pancreas Society staging for pancreatic cancer -- Adjuvant chemotherapy in pancreatic cancer -- Case for adjuvant chemoradiation therapy for pancreatic cancer -- Case for neoadjuvant treatment in pancreatic cancer -- Borderline resectable disease -- Management of cystic neoplasms serous cystic neoplasms mucinous, cystic neoplasms, intraductal paillary mucinous neoplasms -- Laparoscopic surgery for pancreatic neoplasm -- Modern Japanese approach to pancreas cancer -- Development of novel biomarkers -- Inherited genetics of pancreatic cancer and secondary screening -- Gene therapy for pancreatic cancer -- Vaccine therapy and immunotherapy -- Emerging targets in pancreatic cancer.-.
520			_aWorldwide, there are an estimated 232, 000 new cases of pancreatic cancer annually. In the United States, it is the fourth leading cause of cancer death, and approximately 30,000 people die of pancreatic cancer each year. The disease is difficult to diagnose in its early stages, and most patients have incurable disease by the time they present with symptoms. The overall 5-year survival rate for this disease is less than 5%. In organizing this handbook, Dr. Neoptolemos and his co-editors will produce a distinguished Major Reference Work devoted to pancreatic cancer. This handbook will have widespread appeal among clinicians, pathologists and basic scientists who are now struggling to understand this complex and rapidly expanding field. Because of the recent and vast growth in both the clinical and scientific research being done in pancreatic cancer (there is currently an unprecedented investment by academia and industry in this field), each researcher’s knowledge of other specialty areas outside his or her own is now often quite limited. The aim of this book is to place these the tangible advances—those that are indispensable to all working on pancreatic cancer—readily at hand. The book will focus on advances that will not become dated, and the editors will choose authors who are the very best in each area.
590			_aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700	1		_aUrrutia, Raul. _eautor _9303745
700	1		_aAbbruzzese, James L. _eautor _9303746
700	1		_aBüchler, Markus W. _eautor _9303747
710	2		_aSpringerLink (Servicio en línea) _9299170
776	0	8	_iEdición impresa: _z9780387774978
856	4	0	_uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-0-387-77498-5 _zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
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