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001			279478
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008			150903s2007 xxu| o |||| 0|eng d
020			_a9780387767154 _99780387767154
024	7		_a10.1007/9780387767154 _2doi
035			_avtls000332735
039		9	_a201509030235 _bVLOAD _c201404122235 _dVLOAD _c201404092005 _dVLOAD _y201402041036 _zstaff
040			_aMX-SnUAN _bspa _cMX-SnUAN _erda
050		4	_aRC321-580
100	1		_aBagnard, Dominique. _eeditor. _9303816
245	1	0	_aAxon Growth and Guidance / _cedited by Dominique Bagnard.
264		1	_aNew York, NY : _bSpringer New York, _c2007.
300			_brecurso en línea.
336			_atexto _btxt _2rdacontent
337			_acomputadora _bc _2rdamedia
338			_arecurso en línea _bcr _2rdacarrier
347			_aarchivo de texto _bPDF _2rda
490	0		_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v621
500			_aSpringer eBooks
505	0		_aMolecular Mechanisms of Axonal Growth -- Netrins and Their receptors -- Eph Receptors and Ephrin Ligands in Axon Guidance -- Role of Semaphorins during Axon Growth and Guidance -- Slits and Their Receptors -- Neurotrophic Factors: Are They Axon Guidance Molecules? -- The Role of Cell Adhesion Molecules in Axon Growth and Guidance -- Neurotransmitters and the Development of Neuronal Circuits -- The Hedgehog, TGF-?/BMP and Wnt Families of Morphogens in Axon Guidance -- The Role of Cyclic Nucleotides in Axon Guidance -- Membrane Lipid Rafts and Their Role in Axon Guidance -- The Role of Glial Cells in Axon Guidance, Fasciculation and Targeting.
520			_aThis book proposes an updated view of the current knowledge of the molecular and cellular mechanisms ensuring axon growth and guidance. The introductory chapter will remind the readers of all the features of a growth cone and the mechanisms controlling its growth. From there, one enters a fabulous journey with a growth cone, a Tom Thumb story filled with molecular encounters and complex interactions leading to one of the most fantastic developmental achievements: the nervous system wiring. The journey starts with a description of the classical guidance signals such as the netrins, the semaphorins, the ephrins or the Slit family. The question of the exact definition of a guidance signal is addressed in a chapter which discusses whether neurotrophic factors can be considered as guidance cues. This complex question is also considered in a chapter presenting the role of adhesion molecules during axon guidance and the report of compelling evidence for a guidance effect of neurotransmitters. The diversity of the molecular cues used by growth cones to reach their targets is finally illustrated in a chapter describing the unexpected role of morphogenes as direct guidance signals.
590			_aPara consulta fuera de la UANL se requiere clave de acceso remoto.
710	2		_aSpringerLink (Servicio en línea) _9299170
776	0	8	_iEdición impresa: _z9780387767147
856	4	0	_uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-0-387-76715-4 _zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
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999			_c279478 _d279478