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008 150903s2008 xxu| o |||| 0|eng d
020 _a9780387848471
_99780387848471
024 7 _a10.1007/9780387848471
_2doi
035 _avtls000333078
039 9 _a201509030800
_bVLOAD
_c201404122340
_dVLOAD
_c201404092119
_dVLOAD
_y201402041102
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aR-RZ
100 1 _aLaing, Nigel G.
_eeditor.
_9303872
245 1 4 _aThe Sarcomere and Skeletal Muscle Disease /
_cedited by Nigel G. Laing.
264 1 _aNew York, NY :
_bSpringer New York,
_c2008.
300 _axxii, 228 páginas
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v642
500 _aSpringer eBooks
505 0 _aThe Sarcomere and Sarcomerogenesis -- Skeletal Muscle Alpha-Actin Diseases -- Nebulin—A Giant Chameleon -- Skeletal Muscle Disease Due to Mutations in Tropomyosin, Troponin and Cofilin -- Investigations into the Pathobiology of Thin-Filament Myopathies -- Mouse Models for Thin Filament Disease -- Thick Filament Diseases -- Acute Quadriplegic Myopathy: An Acquired “Myosinopathy” -- Third Filament Diseases -- The Z-Disk Diseases -- Intermediate Filament Diseases: Desminopathy -- Muscular Integrity—A Matter of Interlinking Distinct Structures via Plectin -- The Sarcomere and the Nucleus: Functional Links to Hypertrophy, Atrophy and Sarcopenia -- Other Model Organisms for Sarcomeric Muscle Diseases -- Therapeutic Approaches for the Sarcomeric Protein Diseases.
520 _aAlthough best known for its role in heart disease, the sarcomere--the fundamental unit of muscle contraction--is also involved in skeletal muscle diseases. Chapters in The Sarcomere and Skeletal Muscle Disease provide an up-to-date review of diseases caused by mutated proteins in the different sub-compartments of the sarcomere, document the techniques currently being used to investigate the pathobiological bases of the diseases, which remain largely unknown, and discuss possible therapeutic options.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9780387848464
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-0-387-84847-1
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c279506
_d279506