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020 _a9780387689456
_99780387689456
024 7 _a10.1007/9780387689456
_2doi
035 _avtls000331956
039 9 _a201509030203
_bVLOAD
_c201404121958
_dVLOAD
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_dVLOAD
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040 _aMX-SnUAN
_bspa
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_erda
050 4 _aRC261-271
100 1 _aPipas, James.
_eeditor.
_9304632
245 1 0 _aDNA Tumor Viruses /
_cedited by James Pipas, Blossom Damania.
264 1 _aNew York, NY :
_bSpringer US,
_c2009.
300 _brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
500 _aSpringer eBooks
505 0 _aPolyomavirus Life Cycle -- Transformation by Polyomaviruses -- Polyomaviruses and Disease -- The Life Cycle of Human Papillomaviruses -- Papillomavirus Transformation -- Papillomaviruses: Biology, Diversity, and Pathogenesis -- Adenovirus Transformation -- Overview of the Large DNA Tumor Viruses -- Epidemiology of EBV Infection -- EBV Diseases -- The Epstein–Barr Virus Genome -- Epstein–Barr Virus Transforming Proteins: Biologic Properties and Contribution to Oncogenesis -- The Epstein–Barr Virus Lytic Life Cycle -- Epstein–Barr Virus Latent Infection Nuclear Proteins: Genome Maintenance and Regulation of Lymphocyte Cell Growth and Survival -- Epstein–Barr Virus Entry -- EBV Immunotherapy -- KSHV Epidemiology and Subtype Evolution -- to Diseases Associated with Kaposi’s Sarcoma-Associated Herpesvirus -- Organization and Expression of the Kaposi’s Sarcoma-Associated Herpesvirus Genome -- KSHV Latent Genes and Their Regulation -- Regulation of Expression, Mode of Action and Downstream Targets of ORF50 Protein in KSHV Lytic Cycle Activation -- HHV-8/KSHV Proteins Involved in Signaling and Transformation -- KSHV Entry and Infection of Target Cells -- KSHV Immune Evasion -- Non-coding Regulatory RNAs of the DNA Tumor Viruses -- AIDS and Associated Malignancies -- Primate Models for Gammaherpesvirus-Associated Malignancies -- Murine Gammaherpesvirus 68 Infection of Mice: A Small Animal Model for Characterizing Basic Aspects of Gammaherpesvirus Pathogenesis.
520 _aThe DNA tumor viruses are central to many branches of molecular and cellular biology. This very diverse group of viruses attack common cellular pathways, which makes them powerful tools for understanding how multiple complex pathways are integrated. Additionally, the unique mechanisms employed by each viral system to alter cellular functions serve as powerful molecular probes for the identification of new targets and pathways. The scientific impact of the DNA tumor viruses extends far beyond their etiologic role in human cancers, or their contributions to our basic understanding of the cellular pathways that drive tumorigenesis. Currently, research on these viruses lies at the interface of cancer and the innate and adaptive immune response, investigating how infectious agents influence, evade, and utilize systems that regulate these processes. Thus, DNA tumor viruses serve as models for the systems biology of host-pathogen interactions. "DNA Tumor Viruses," edited by Blossom Damania and James M. Pipas, summarizes recent advances in our understanding of this diverse and fascinating collection of viruses.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700 1 _aDamania, Blossom.
_eeditor.
_9304633
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9780387689449
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-0-387-68945-6
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c280003
_d280003