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008 150903s2008 xxu| o |||| 0|eng d
020 _a9780387691329
_99780387691329
024 7 _a10.1007/9780387691329
_2doi
035 _avtls000331991
039 9 _a201509030212
_bVLOAD
_c201404122005
_dVLOAD
_c201404091731
_dVLOAD
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_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aRC261-271
100 1 _aLi, Shaoguang.
_eeditor.
_9304732
245 1 0 _aMouse Models of Human Blood Cancers :
_bBasic Research and Pre-clinical Applications /
_cedited by Shaoguang Li.
264 1 _aNew York, NY :
_bSpringer US,
_c2008.
300 _brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
500 _aSpringer eBooks
505 0 _aMouse Models of Myeloproliferative Disease Associated with Mutant JAK2 Tyrosine Kinase: Insights into Pathophysiology and Therapy -- Genetic Modeling of Human Blood Cancers in Mice -- Murine Models of Hematopoietic Disease: Pathologic Analysis and Characterization -- Mechanisms of DNA Double-Strand Break Repair in Hematopoietic Homeostasis and Oncogenesis -- Modeling Human Leukemia Using Immune-Compromised Mice -- Dietary Restriction: A Model System Probing the Cell Fate Decision Between Cancer and Senescence -- Modeling Human Philadelphia Chromosome-Positive Leukemia in Mice -- Mouse Models of Human Mature B-Cell and Plasma Cell Neoplasms -- Genetic and Virological Predisposition to Pre-B Lymphomagenesis in SL/Kh -- Animal Cancer Models in Anticancer Drug Discovery and Development -- DGL Global Strategies in DNA Microarray Gene Expression Analysis and Data Mining for Human Blood Cancers.
520 _aAlthough it remains an open question among some people whether mice and humans are similar in disease development, the laboratory mouse has emerged as the preeminent animal model for human diseases. This is underscored by the recently completed mouse and human genome projects, which have revealed that mice and humans share the vast majority of their genes, and thus get many of the same diseases, and for the same reasons. Emphasizing why mouse models are valuable in vivo systems for understanding disease mechanisms and developing therapeutic strategies for human blood cancers, "Mouse Models of Human Blood Cancers: Basic Research and Pre-clinical Applications," edited by Shaoguang Li, aims on presenting thorough analyses of the pathological features and the molecular bases of several major types of blood cancer and to describe translational research using mouse cancer models.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9780387691305
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-0-387-69132-9
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c280058
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