000 03734nam a22003735i 4500
001 280090
003 MX-SnUAN
005 20160429154009.0
007 cr nn 008mamaa
008 150903s2007 xxu| o |||| 0|eng d
020 _a9780387687339
_99780387687339
024 7 _a10.1007/9780387687339
_2doi
035 _avtls000331912
039 9 _a201509030208
_bVLOAD
_c201404121950
_dVLOAD
_c201404091717
_dVLOAD
_y201402041016
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aQH323.5
100 1 _aWodarz, Dominik.
_eeditor.
_9304785
245 1 0 _aKiller Cell Dynamics :
_bMathematical and Computational Approaches to Immunology /
_cedited by Dominik Wodarz.
264 1 _aNew York, NY :
_bSpringer New York,
_c2007.
300 _axiii, 220 páginas
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aInterdisciplinary Applied Mathematics,
_x0939-6047 ;
_v32
500 _aSpringer eBooks
505 0 _aViruses and Immune Responses: A Dynamical View -- Models of CTL Responses and Correlates of Virus Control -- CTL Memory -- CD4 T Cell Help -- Immunodominance -- Multiple Infections and CTL Dynamics -- Control versus CTL-Induced Pathology -- Lytic versus Nonlytic Activity -- Dynamical Interactions between CTL and Antibody Responses -- Effector Molecules and CTL Homeostasis -- Virus-Induced Subversion of CTL Responses -- Boosting Immunity against Immunosuppressive Infections -- Evolutionary Aspects of Immunity.
520 _aThis book reviews how mathematics can be used in combination with biological data in order to improve understanding of how the immune system works. This is illustrated largely in the context of viral infections. Mathematical models allow scientists to capture complex biological interactions in a clear mathematical language and to follow them to their precise logical conclusions. This can give rise to counter-intuitive insights which would not be attained by experiments alone, and can be used for the design of further experiments in order to address the mathematical results. This book provides both an introduction to the field of mathematical immunology, and an overview of many topics which are the subject of current research, covering a broad variety of immunological topics. It starts with basic principles of immunology and covers the dynamical interactions between the immune system and specific viral infections, including important human pathogens such as HIV. General biological and mathematical background material to both virus infection and immune system dynamics is provided, and each chapter begins with a simple introduction to the biological questions examined. This book is intended for an interdisciplinary audience. It explains the concept of mathematical modeling in immunology and shows how modeling has been used to address specific questions. It is intended both for the mathematical biologists who are interested in immunology, and for the biological readership that is interested in the use of mathematical models in immunology. Dominik Wodarz is an Associate Professor at the Department of Ecology and Evolutionary Biology at the University of California, Irvine.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9780387308937
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-0-387-68733-9
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c280090
_d280090