| 000 | 02502nam a22003735i 4500 | ||
|---|---|---|---|
| 001 | 280152 | ||
| 003 | MX-SnUAN | ||
| 005 | 20160429154012.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 150903s2009 xxu| o |||| 0|eng d | ||
| 020 |
_a9780387691473 _99780387691473 |
||
| 024 | 7 |
_a10.1007/9780387691473 _2doi |
|
| 035 | _avtls000331994 | ||
| 039 | 9 |
_a201509030212 _bVLOAD _c201404122005 _dVLOAD _c201404091732 _dVLOAD _y201402041018 _zstaff |
|
| 040 |
_aMX-SnUAN _bspa _cMX-SnUAN _erda |
||
| 050 | 4 | _aRC261-271 | |
| 100 | 1 |
_aRubin, Eric. _eeditor. _9304899 |
|
| 245 | 1 | 0 |
_aModulation of Protein Stability in Cancer Therapy / _cedited by Eric Rubin, Kathleen Sakamoto. |
| 264 | 1 |
_aNew York, NY : _bSpringer US, _c2009. |
|
| 300 | _brecurso en línea. | ||
| 336 |
_atexto _btxt _2rdacontent |
||
| 337 |
_acomputadora _bc _2rdamedia |
||
| 338 |
_arecurso en línea _bcr _2rdacarrier |
||
| 347 |
_aarchivo de texto _bPDF _2rda |
||
| 500 | _aSpringer eBooks | ||
| 505 | 0 | _aUbiquitin Ligases and Cancer -- The 26S Proteasome as a Therapeutic Target in Cancer: Beyond Protease Inhibitors? -- Targeting HAUSP: Killing Two Birds with One Stone -- Modulation of Protein Stability: Targeting the VHL Pathway -- Interrelationship of the Fanconi Anemia/BRCA Pathway -- Targeting the Sumoylation Pathway -- Proteasome Inhibitors -- Targeting Deubiquitinating Enzymes -- Proteolysis Targeting Chimeric Molecules. | |
| 520 | _aThis book contains chapters written by experts in the field of the ubiquitin proteasome system and cancer. The authors have summarized current information on ubiquitin ligases and proteasomes as potential targets for cancer therapy. Topics covered in the book include an overview of ubiquitin ligases, deubiquitinating enzymes, and the proteasome. Specific diseases resulting from deregulated ubiquitin ligases, such as Von-Hippel-Lindau disease and Fanconi anemia are also discussed. Finally, novel approaches and drugs to target proteins involved in sumoylation, ubiquitination, and degradation are described. | ||
| 590 | _aPara consulta fuera de la UANL se requiere clave de acceso remoto. | ||
| 700 | 1 |
_aSakamoto, Kathleen. _eeditor. _9304900 |
|
| 710 | 2 |
_aSpringerLink (Servicio en línea) _9299170 |
|
| 776 | 0 | 8 |
_iEdición impresa: _z9780387691435 |
| 856 | 4 | 0 |
_uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-0-387-69147-3 _zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL) |
| 942 | _c14 | ||
| 999 |
_c280152 _d280152 |
||