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020 _a9780387894560
_99780387894560
024 7 _a10.1007/b135974
_2doi
035 _avtls000333293
039 9 _a201509030204
_bVLOAD
_c201405070502
_dVLOAD
_y201402041107
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aQR355-502
100 1 _aRaney, Kevin D.
_eeditor.
_9305474
245 1 0 _aViral Genome Replication /
_cedited by Kevin D. Raney, Matthias Gotte, Craig E. Cameron.
264 1 _aBoston, MA :
_bSpringer US,
_c2009.
300 _brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
500 _aSpringer eBooks
505 0 _aGenome replication strategies -- Model of Picornavirus RNA Replication -- Coronavirus Genome Replication -- Flaviviruses -- Hepatitis C Virus Genome Replication -- Brome Mosaic Virus RNA Replication and Transcription -- Retroviruses -- Hepadnaviral Genomic Replication -- Rhabdoviruses -- Orthomyxovirus Genome Transcription and Replication -- Arenaviruses: Genome Replication Strategies -- Core-Associated Genome Replication Mechanisms of dsRNA Viruses -- Poxviruses -- Herpesvirus Genome Replication -- Host Factors Promoting Viral RNA Replication -- Host Factors that Restrict Retrovirus Replication -- Elements, factors and enzymes: Structure-function and mechanism -- T4 Phage Replisome -- Atomic Structure of the Herpes Simplex Virus 1 DNA Polymerase -- RNA Virus Polymerases -- Human Immunodeficiency Virus Reverse Transcriptase -- Viral Helicases -- Integrase: Structure, Function, and Mechanism -- Antivirals: Targets, mechanisms and resistance -- Viral DNA Polymerase Inhibitors -- Viral RNA Polymerase Inhibitors -- HIV-1 Reverse Transcriptase Inhibitors and Mechanisms of Resistance -- Lethal Mutagenesis -- Clinical Implications of Reverse Transcriptase Inhibitor Resistance.
520 _aCurrently, there is no single source that permits comparison of the factors, elements, enzymes and/or mechanisms employed by different classes of viruses for genome replication. As a result, we (and our students) often restrict our focus to our particular system, missing out on the opportunity to define unifying themes in viral genome replication or benefit from the advances in other systems. For example, extraordinary biological and experimental paradigms that have been established over the past five years for the DNA replication systems of bacteriophage T4 and T7 will likely be of great value to anyone interested in studying a replisome from any virus. These studies could easily go unnoticed by animal RNA and DNA virologists. It is our hope that this monograph will cross-fertilize and invigorate the field, as well as encourage students into this area of research.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700 1 _aGotte, Matthias.
_eeditor.
_9305475
700 1 _aCameron, Craig E.
_eeditor.
_9305476
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9780387894256
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/b135974
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c280507
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