000 03364nam a22003735i 4500
001 280651
003 MX-SnUAN
005 20160429154032.0
007 cr nn 008mamaa
008 150903s2010 xxu| o |||| 0|eng d
020 _a9780387938462
_99780387938462
024 7 _a10.1007/9780387938462
_2doi
035 _avtls000333396
039 9 _a201509030802
_bVLOAD
_c201404130430
_dVLOAD
_c201404092219
_dVLOAD
_y201402041110
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aRC254-282
100 1 _aChung, Daniel C.
_eeditor.
_9305727
245 1 0 _aPrinciples of Clinical Cancer Genetics :
_bA Handbook from the Massachusetts General Hospital /
_cedited by Daniel C. Chung, Daniel A. Haber.
264 1 _aBoston, MA :
_bSpringer US :
_bImprint: Springer,
_c2010.
300 _ax, 227 páginas 48 ilustraciones, 46 ilustraciones en color.
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
500 _aSpringer eBooks
505 0 _aBasic Principles of Cancer Genetics -- Principles of Cancer Genetic Counseling and Genetic Testing -- Genetics of Hereditary Breast Cancer -- Surgical Management of Hereditary Breast and Ovarian Cancer -- Hereditary Colon Cancer: Colonic Polyposis Syndromes -- Hereditary Colon Cancer: Lynch Syndrome -- Hereditary Pancreatic Cancer -- Hereditary Diffuse Gastric Cancer -- Familial Renal Cell Cancers and Pheochromocytomas -- Familial Atypical Mole Melanoma (FAMM) Syndrome -- Multiple Endocrine Neoplasia -- Pediatric Malignancies: Retinoblastoma and Wilms’ Tumor -- Neurofibromatosis and Schwannomatosis -- The HapMap Project and Low-Penetrance Cancer Susceptibility Alleles -- Somatic Genetic Alterations and Implications for Targeted Therapies in Cancer (GIST, CML, Lung Cancer).
520 _aAdvances in genetics are transforming estimates of an individual’s risk of developing cancer and approaches to prevention and management of cancer in those who may have increased susceptibility. Identifying and caring for patients with hereditary cancer syndromes and their family members present a complex clinical, scientific and social challenge. This textbook, by leading experts at Massachusetts General Hospital Cancer Center, highlights the current understanding of the genetics of hereditary cancers of the breast, ovary, colorectum, stomach, pancreas, kidney, skin, and endocrine organs. Practical guidelines for the use of genetic testing, cancer screening and surveillance, prophylactic surgery, and promising targeted therapeutic agents are discussed. In addition, ongoing research involving genome-wide screens to identify novel modest risk-associated genetic loci are explored, along with new approaches to the application of genetic markers in guiding therapeutic options.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700 1 _aHaber, Daniel A.
_eeditor.
_9305728
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9780387938448
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-0-387-93846-2
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c280651
_d280651