000			03602nam a22003735i 4500
001			280690
003			MX-SnUAN
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007			cr nn 008mamaa
008			150903s2009 xxu| o |||| 0|eng d
020			_a9780387938776 _99780387938776
024	7		_a10.1007/9780387938776 _2doi
035			_avtls000333401
039		9	_a201509030802 _bVLOAD _c201404130431 _dVLOAD _c201404092220 _dVLOAD _y201402041110 _zstaff
040			_aMX-SnUAN _bspa _cMX-SnUAN _erda
050		4	_aR-RZ
100	1		_aSegev, Nava. _eautor _9305799
245	1	0	_aTrafficking Inside Cells : _bPathways, Mechanisms and Regulation / _cby Nava Segev.
264		1	_aNew York, NY : _bSpringer New York, _c2009.
300			_brecurso en línea.
336			_atexto _btxt _2rdacontent
337			_acomputadora _bc _2rdamedia
338			_arecurso en línea _bcr _2rdacarrier
347			_aarchivo de texto _bPDF _2rda
490	0		_aMolecular Biology Intelligence Unit
500			_aSpringer eBooks
505	0		_aCompartments and Pathways -- Overview of Intracellular Compartments and Trafficking Pathways -- How We Study Protein Transport -- The Golgi Apparatus -- The Endocytic Pathway -- Regulated Secretion -- Mechanisms -- Overview of Protein Trafficking Mechanisms -- Entry into the Endoplasmic Reticulum: Protein Translocation, Folding and Quality Control -- COP-Mediated Vesicle Transport -- Clathrin-Mediated Endocytosis -- Biogenesis of Dense-Core Secretory Granules -- Lipid-Dependent Membrane Remodelling in Protein Trafficking -- Carrier Motility -- Tethering Factors -- Intracellular Membrane Fusion -- Regulation and Coordination with Other Cellular Processes -- Regulation and Coordination of Intracellular Trafficking: An Overview -- Regulation of Protein Trafficking by GTP-Binding Proteins -- Posttranslational Control of Protein Trafficking in the Post-Golgi Secretory and Endocytic Pathway -- Actin Doesn’t Do the Locomotion: Secretion Drives Cell Polarization -- Intracellular Trafficking and Signaling: The Role of Endocytic Rab GTPase -- The Exocytic Pathway and Development.
520			_aThe human body is made up of trillions of tiny cells that cannot be seen by the naked eye. The functioning units inside these cells are macromolecules that need to travel in the three-dimensional cell-space to distances ten thousand times their size. This movement is highly ordered, requires energy and takes place on molecular tracks that serve as a sophisticated transport system—somewhat equivalent to the multimodal rail-highway-river networks of large metropolises. All the systems of the human body depend on the efficient delivery of macromolecules to their right destination at the right time—both within and between cells. Breakdown of this traffic system results in a variety of diseases including diabetes, cancer and heart disease, as well as immunological, neurological and developmental disorders. During the last half a century, scientists have made a quantum leap in unraveling the mysteries of trafficking inside cells. The three sections of this book together cover the past, present and future of this rapidly developing and intriguing field.
590			_aPara consulta fuera de la UANL se requiere clave de acceso remoto.
710	2		_aSpringerLink (Servicio en línea) _9299170
776	0	8	_iEdición impresa: _z9780387938769
856	4	0	_uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-0-387-93877-6 _zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
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999			_c280690 _d280690