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020 _a9781402022173
_99781402022173
024 7 _a10.1007/1402022174
_2doi
035 _avtls000334077
039 9 _a201509030232
_bVLOAD
_c201404120643
_dVLOAD
_c201404090423
_dVLOAD
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_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aQL801-950.9
100 1 _aAl-Rubeai, Mohamed.
_eeditor.
_9307051
245 1 0 _aCell Engineering :
_bApoptosis /
_cedited by Mohamed Al-Rubeai, Martin Fussenegger.
264 1 _aDordrecht :
_bSpringer Netherlands,
_c2005.
300 _aIx, 335 páginas
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aCell Engineering,
_x1389-6946 ;
_v4
500 _aSpringer eBooks
505 0 _aCaspase Regulation at the Molecular Level -- The Bcl-2 Family -- The IGF-1 Receptor in Cell Survival: Signalling and Regulation -- Apoptosis in Hepatocytes -- Programmed Cell Death in Plants During Development and Stress Responses -- A Systems View of Cell Death -- The Role of Caspases in Apoptosis and Their Inhibition in Mammalian Cell Culture -- Improvement of Industrial Cell Culture Processes by Caspase-9 Dominant Negative and Other Apoptotic Inhibitors -- Therapeutic Small Molecule Inhibitors of Bcl-2 -- Apoptosis Control Based on Down-Regulating the Inhibitor-of-Apoptosis (IAP) Proteins: Xiap Antisense and Other Approaches -- Monitoring of Apoptosis -- Molecular Imaging of Programmed Cell Death; from Basic Mechanisms to Clinical Applications.
520 _aThe series Cell Engineering is the first and only major reference work on the development of cellular systems for the production of recombinant glycoproteins, gene and cell therapies, drug screening and tissue engineering. This volume on "Apoptosis" is intended to review the state-of-the-art with in-depth assessments of this type of programmed cell death. The aim of the volume is to make the recent developments in apoptotic research readily accessible to biologists, biotechnologists and cellular engineers. The implication of apoptosis in the suppression of diseases and prolonging survival of cells in culture is presented to indicate the great potential of apoptotic research for drug production and the development of human therapies. All chapters are written as self-contained treatments of the important topics in apoptosis that are presented on an essential information basis. Topics covered range from understanding the role of signalling and effector molecules, mathematical modelling of cell death, RNAi tools in apoptosis research, to monitoring and imaging of apoptosis. This volume will be an invaluable resource for biotechnologists and researchers in apoptosis, cell biology, cell culture and molecular medicine.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700 1 _aFussenegger, Martin.
_eeditor.
_9307052
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9781402022166
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/1-4020-2217-4
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c281407
_d281407