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008			150903s2005 ne | o |||| 0|eng d
020			_a9781402033025 _99781402033025
024	7		_a10.1007/1402033028 _2doi
035			_avtls000334300
039		9	_a201509030223 _bVLOAD _c201404120723 _dVLOAD _c201404090503 _dVLOAD _y201402041144 _zstaff
040			_aMX-SnUAN _bspa _cMX-SnUAN _erda
050		4	_aRC261-271
100	1		_aSluyser, Mels. _eautor _9307086
245	1	0	_aApplication of Apoptosis to Cancer Treatment / _cby Mels Sluyser.
264		1	_aDordrecht : _bSpringer Netherlands, _c2005.
300			_avii, 370 páginas _brecurso en línea.
336			_atexto _btxt _2rdacontent
337			_acomputadora _bc _2rdamedia
338			_arecurso en línea _bcr _2rdacarrier
347			_aarchivo de texto _bPDF _2rda
500			_aSpringer eBooks
505	0		_aDisfunction of the Apoptotic Pathway in Cancer Cells -- Calcium Signaling and Apoptosis Resistance of Cancer Cells -- Cell Clearance and Cancer -- Specific, Pro-Poptotic Cell-Signaling: Design of Novel, Recombinant Targeted Antitumor Agents Operating Exclusively Through Modulation of Cellular Apoptotic Events -- Targeting Oncogenes Which Regulate Apoptosis -- Targeting Cyclins to Cause Cancer Cell Apoptosis -- Apoptosis Induction By Tumor- Targeted Toxins -- Targeting Cell-Death Pathways in Multiple Myeloma: Therapeutic Implications -- Cephalostatin 1-Induced Apoptosis in Tumor Cells -- Hamlet; A Novel Tool to Identify Apoptotic Pathways in Tumor Cells -- Cancer Immunotherapy: On the Trail of a Cure? -- Histone Deacetylase Inhibitors as a Treatment of Trail-Resistant Cancers -- Basis of Cell Kill Following Clinical Radiotherapy -- Imaging of Apoptotic Cells in vivo -- Apoptosis-Inducing Anticancer Drugs in Clinical Trials.
520			_aNovel drugs are being developed which interact with the programmed cell death (apoptotic) machinery in cancer cells, thereby causing these cells to commit suicide and to be removed from the body. Research is also directed to investigate why the cancer cells sometimes lose the ability to undergo apoptosis after a certain period of time and methods are being developed to reactivate this cell death process. This book is intended for workers in the field and clinicians as a useful guide of the state of affairs in this exciting field which may offer more effective possibilities for treatment of cancer patients. Mels Sluyser is the Editor of the journals APOPTOSIS and ANTI-CANCER DRUGS. He brings together a collection of papers written by the world’s leading experts in these fields.
590			_aPara consulta fuera de la UANL se requiere clave de acceso remoto.
710	2		_aSpringerLink (Servicio en línea) _9299170
776	0	8	_iEdición impresa: _z9781402033032
856	4	0	_uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/1-4020-3302-8 _zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
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999			_c281422 _d281422