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020 _a9781402052521
_99781402052521
024 7 _a10.1007/1402052529
_2doi
035 _avtls000335099
039 9 _a201509030230
_bVLOAD
_c201404120922
_dVLOAD
_c201404090700
_dVLOAD
_y201402041251
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aQD431-431.7
100 1 _aAl-Rubeai, Mohamed.
_eeditor.
_9307051
245 1 0 _aSystems Biology /
_cedited by Mohamed Al-Rubeai, Martin Fussenegger.
264 1 _aDordrecht :
_bSpringer Netherlands,
_c2007.
300 _aviii, 423 páginas
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aCell Engineering,
_x1389-6946 ;
_v5
500 _aSpringer eBooks
505 0 _aStructural Genomics -- RNA Interference in Haematopoietic and Leukaemic Cells -- Genomics and Proteomics of Chinese Hamster Ovary (CHO) Cells -- The Unfolded Protein Response -- Engineering of Cell Proliferation Via Myc Modulation -- The Molecular Response(s) During Cellular Adaptation to, and Recovery from, Sub-Physiological Temperatures -- Molecular Response to Osmotic Shock -- Metabolomics -- Metabolic Flux Analysis of Mammalian Cells -- Metabolic Engineering -- Chemical Organisation Theory -- Prokaryotic Systems Biology.
520 _aA comprehensive guide to the revolutionary area of systems biology and its application in cell culture engineering, this volume presents an overall picture of the current topics central to structural and functional genomics, proteomics, metabolomics and bioinformatics, including such hot topics as RNAi, metabolic engineering and unfolded protein response. It includes reviews of the cellular response of environmental modulation such as low temperature and osmolarity, critical assessments of the applications of metabolomics and fluxomics approaches, examination of the utility of modulation of key genes and a presentation of a theory of chemical organisation which provides a new view of the system's structure. The clearly written chapters by experts in the field describe methods applicable to investigating the unique facets of cell culture. The book should be of interest to all those working in cell culture development and drug discovery in pharmaceutical and biotechnology companies as well as in academic institutions. It provides an invaluable resource for students and researchers in biotechnology, cell culture, genomics and bioinformatics.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700 1 _aFussenegger, Martin.
_eeditor.
_9307052
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9781402052514
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/1-4020-5252-9
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c282260
_d282260