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007 cr nn 008mamaa
008 150903s2008 ne | o |||| 0|eng d
020 _a9781402061912
_99781402061912
024 7 _a10.1007/9781402061912
_2doi
035 _avtls000335513
039 9 _a201509030238
_bVLOAD
_c201404300302
_dVLOAD
_y201402041302
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aRB155-155.8
100 1 _aCarafoli, Ernesto.
_eeditor.
_9309776
245 1 0 _aCalcium Signalling and Disease :
_bMolecular Pathology of Calcium /
_cedited by Ernesto Carafoli, Marisa Brini.
264 1 _aDordrecht :
_bSpringer Netherlands,
_c2008.
300 _axii, 592 páginas
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aSubcellular Biochemistry,
_x0306-0225 ;
_v45
500 _aSpringer eBooks
505 0 _aAnnexinopathies -- Calpains and Human Disease -- Gelsolin and Diseases -- Guanylate Cyclase-Activating Proteins and Retina Disease -- Pathologies Involving the S100 Proteins and Rage -- The Calcium-Sensing Receptor: Physiology, Pathophysiology and Car-Based Therapeutics -- Physiological Roles Of The Ca2+/Cam-Dependent Protein kinase Cascade In Health and Disease -- Calcium Channelopathies: Voltage-Gated Calcium Channels -- Trp Channels In Disease -- Diseases associated with altered ryanodine receptor activity -- Inositol 1,4,5-tripshosphate receptor, calcium signalling and huntington’s disease -- Serca pumps and human diseases -- The plasma membrane calcium ATPase and disease -- Diseases involving the Golgi calcium pump -- Calcium signalling and cancer cell growth -- Calcium Misregulation and the Pathogenesis of Muscular Dystrophy -- Calcium and Cell Death -- Calcium and Cell Death: The Mitochondrial Connection -- Role of Calcium in the Pathogenesis of Alzheimer’s Disease and Transgenic Models -- Calcium and Cardiomyopathies -- Calcium Signalling and Calcium Transport in Bone Disease.
520 _aThis topic is a new entry in the area of cellular calcium signaling: yet, it now spans the entire area, with discoveries that cover both genetic and acquired pathologies, even offering glimpses in the direction of therapy. Cellular calcium homeostasis, and thus calcium signalling, is mainly regulated by membrane intrinsic proteins and calcium sensor proteins. Both classes may be involved in pathological processes that affect both human and animals, ranging from common and important diseases (e.g. migraine, diabetes, epilepsia, manic depression, infertility, various types of cancer, Alzheimer’s disease, muscular dystrophy) to rare genetic conditions (e.g., a number of genetic heart conditions, autoimmune retinopathies, night blindness, hereditary amyloid polyneuropathy, malignant hyperthermia, cerebellar ataxia, atherothrombotic disease). Clearly, the topic has now become not only very large, but also very stimulating. Its extensive critical coverage is likely to eventually stimulate fruitful interdisciplinary discussions.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700 1 _aBrini, Marisa.
_eeditor.
_9309777
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9781402061905
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-1-4020-6191-2
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c282780
_d282780