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001 282968
003 MX-SnUAN
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007 cr nn 008mamaa
008 150903s2008 ne | o |||| 0|eng d
020 _a9781402083990
_99781402083990
024 7 _a10.1007/9781402083990
_2doi
035 _avtls000335977
039 9 _a201509030255
_bVLOAD
_c201404300309
_dVLOAD
_y201402041337
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aRM1-950
100 1 _aValacchi, Giuseppe.
_eeditor.
_9310137
245 1 0 _aOxidants in Biology :
_bA Question of Balance /
_cedited by Giuseppe Valacchi, Paul A. Davis.
264 1 _aDordrecht :
_bSpringer Netherlands,
_c2008.
300 _brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
500 _aSpringer eBooks
505 0 _aOld Players -- Hydrogen Peroxide: The Good, The Bad, and The Ugly -- Peroxynitrite: A Key Molecule in Skin Tissue Response to Different Types of Stress -- Cellular and Environmental Electrophiles: Balancing Redox Signaling, Inflammation, and Cell Death Pathways -- The Role of Reactive Nitrogen Species (RNS) in the Activation of Nuclear Factor Kappa B (NFkB) and Its Implications for Biological Systems: The Question of Balance -- Neutrophil-Derived Oxidants as Modulators of Polyunsaturated Fatty Acid Metabolism -- Fatty Acids in the Modulation of Reactive Oxygen Species Balance in Cancer -- The Question of Balance: The Interaction Between Blood and Ozone -- Iron and Erythrocytes: Physiological and Pathophysiological Aspects -- The Adventures of Superoxide Dismutase in Health and Disease: Superoxide in the Balance -- Glutathione Metabolism: Favorable Versus Unfavorable Effects -- Dual Roles of Oxidative Stress in the Lungs -- Antioxidants: How They Work -- New Players -- The Role of DUOX Isozymes in the Respiratory Tract Epithelium -- Hypertension, Diabetes, Oxidative Stress, and Cardiovascular Remodeling: Making the Connection with p66shc -- A Role of BRCA1-Associated Protein BARD1 in Oxidative Stress Response and Signaling and Proliferation Control -- Postprandial Events as a Trigger for Redox Unbalance: Role of Dietary Lipid Hydroperoxides and Antioxidants -- F2-Isoprostanes: Markers and Mediators of an Imbalanced Redox Status in the Liver.
520 _aOxidants, like other aspects of life, involves tradeoffs. Oxidants, whether intentionally produced or by-products of normal metabolism can either mediate a variety of critical biological processes but when present inappropriately cause extensive damage to biological molecules (DNA, proteins, and lipids). These effects can lead to either damage that is a major contributor to aging and degenerative diseases (or to other diseases such as cancer, cardiovascular disease, immune-system decline, brain dysfunction, and cataracts) or normal physiological function- tissue repair, defense against pathogens and cellular proliferation. On the other hand the body is equipped with a complex antioxidant/oxidant handling system which includes both enzymatic and nonenzymatic (i.e. small molecules such as flavonoids, ascorbate, tocopherol, and carotenoids) produced endogenously or derived from the diet. This book focuses on how the same molecules can have favorable or noxious effects depending on location, level and timing. Each chapter focuses on one particular molecule or oxidant/antioxidant system and provides a state of the art review of the current understanding regarding both positive and negative actions of the system under review.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700 1 _aDavis, Paul A.
_eeditor.
_9310138
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9781402083983
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-1-4020-8399-0
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
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999 _c282968
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