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001 285495
003 MX-SnUAN
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008 150903s2010 xxu| o |||| 0|eng d
020 _a9781441978233
_99781441978233
024 7 _a10.1007/9781441978233
_2doi
035 _avtls000339073
039 9 _a201509030312
_bVLOAD
_c201404300354
_dVLOAD
_y201402060926
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aR-RZ
100 1 _aGroßhans, Helge.
_eeditor.
_9313701
245 1 0 _aRegulation of microRNAs /
_cedited by Helge Großhans.
264 1 _aNew York, NY :
_bSpringer US,
_c2010.
300 _axvI, 160 páginas 35 ilustraciones, 6 ilustraciones en color.
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v700
500 _aSpringer eBooks
505 0 _amicroRNA Biogenesis and Function -- Regulation of pri-miRNA Processing Through Smads -- Stimulation of pri-miR-18a Processing by hnRNP A1 -- KSRP Promotes the Maturation of a Group of miRNA Precuresors -- Hormonal Repression of miRNA Biosynthesis Through a Nuclear Steroid Hormone Receptor -- Autoregulatory Mechanisms Controlling the Microprocessor -- Regulation of pre-miRNA Processing -- The Effect of RNA Editing and ADARs on miRNA Biogenesis and Function -- miRNAs Need a Trim -- Properties of the Regulatory RNA-Binding Protein HuR and its Role in Controlling miRNA Repression -- Turnover of Mature miRNAs and siRNAs in Plants and Algae -- MicroRNases and the Regulated Degradation of Mature Animal miRNAs.
520 _aGiven this pervasiveness and importance of miRNA-mediated gene regulation, it should come as little surprise that miRNAs themselves are also highly regulated. However, the recent explosion of knowledge on this topic has been remarkable, providing a primary motivation for publication of this book. As miRNAs are transcribed by RNA polymerase II, the enzyme that also generates mRNAs, it was perhaps not unexpected that miRNA transcription would be subject to regulation, and we have willfully mitted this aspect from this monograph. However, what has been unexpected is the extent of post-transcriptional regulation of miRNAs that is illustrated in this book.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9781441978226
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-1-4419-7823-3
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c285495
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