000 04155nam a22003975i 4500
001 286191
003 MX-SnUAN
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007 cr nn 008mamaa
008 150903s2012 xxu| o |||| 0|eng d
020 _a9781441957740
_99781441957740
024 7 _a10.1007/9781441957740
_2doi
035 _avtls000338481
039 9 _a201509030815
_bVLOAD
_c201404300346
_dVLOAD
_y201402060911
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aRC927-927.5
100 1 _aVarga, John.
_eeditor.
_9314726
245 1 0 _aScleroderma :
_bFrom Pathogenesis to Comprehensive Management /
_cedited by John Varga, Christopher P. Denton, Fredrick M. Wigley.
250 _a1.
264 1 _aBoston, MA :
_bSpringer US,
_c2012.
300 _axx, 689 páginas 163 ilustraciones, 131 ilustraciones en color.
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
500 _aSpringer eBooks
505 0 _aForeword -- Preface -- Historical Perspective.-Therapeutic evolution: a professor’s view -- Overview: Epidemiology, Genetics and Classification.-Epidemiology and Environmental Risk Factors.- Genetic Factors -- Disease Subsets in Clinical Practice.-Evolving Concepts of Diagnosis and Classification -- Disease Classification using Molecular Signatures.-Localized Scleroderma -- Juvenile Systemic Scleroderma.-Scleroderma Mimics -- Localized Forms of Scleroderma in Adults.-Overview: Integrated Pathogenesis -- Immunological Mechanisms.-Innate Immunity -- Autoantibodies in Pathogenesis -- The Clinical Aspects of Autoantibodies -- Mechanisms of Vascular Disease.-Vascular Biomarkers -- Mechanisms of Fibrosis -- Fibrosis: Insights from the stiff skin syndrome -- Biomarkers of Fibrosis -- Overview of Animal Models.-Overview: Cardiovascular Manifestations and Management.-Raynaud Phenomenon.-Nailfold Capillaroscopy -- Systemic Vascular Disease -- Scleroderma Renal Crisis -- Cardiac Involvement.-Erectile Dysfunction.-Overview: Pulmonary manifestations and management.-Clinical Assessment of Lung Disease -- Computerized Tomography of Interstitial Lung Disease.-Treatment of interstitial lung disease.-Clinical Assessment of Pulmonary Hypertension.-Treatment of Pulmonary Hypertension -- Complex Challenges of Pulmonary Hypertension -- Overview: Gastrointestinal Manifestations and Management -- Upper Gastrointestinal Tract.-Small and Large Intestinal Involvement.-Evaluation and Management of Skin Disease.-Skeletal Muscle Involvement.-  Tendons, Joints and Bone -- Pregnancy.-Overlooked Manifestations -- Principles of Management.-Immunomodulatory Therapies.-Cell-Based Therapies -- Investigative Approaches to Drug Therapy.-Complementary and alternate medicine approaches.-Physical and occupational therapy -- Evaluation and Management of Psychosocial Issues.-Issues in Clinical Trial Design -- Measuring Disease Activity -- Patient Reported Outcomes. .
520 _aThis essential resource presents the most up-to-date information on scleroderma. A clear and concise synthesis of current concepts in pathogenesis and modern approaches to management, this book is comprised of the authoritative work of international experts. With an integrated multidisciplinary approach to comprehensive care, this book is easily accessible for health care professionals in many fields. It is a valuable resource for rheumatologists, pulmonologists, cardiologists, gastroenterologists, nephrologists and all those involved in the care of scleroderma patients.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700 1 _aDenton, Christopher P.
_eeditor.
_9306223
700 1 _aWigley, Fredrick M.
_eeditor.
_9314727
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9781441957733
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-1-4419-5774-0
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c286191
_d286191