000 04145nam a22003975i 4500
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008 150903s2013 xxk| o |||| 0|eng d
020 _a9781447152989
_99781447152989
024 7 _a10.1007/9781447152989
_2doi
035 _avtls000340063
039 9 _a201509030842
_bVLOAD
_c201404300409
_dVLOAD
_y201402061016
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aQH324.2-324.25
100 1 _aChauve, Cedric.
_eeditor.
_9315005
245 1 0 _aModels and Algorithms for Genome Evolution /
_cedited by Cedric Chauve, Nadia El-Mabrouk, Eric Tannier.
264 1 _aLondon :
_bSpringer London :
_bImprint: Springer,
_c2013.
300 _axii, 328 páginas 86 ilustraciones, 45 ilustraciones en color.
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aComputational Biology,
_x1568-2684 ;
_v19
500 _aSpringer eBooks
505 0 _aPart I: Emergence of Standard Algorithms -- What's Behind Blast -- Forty Years of Model-Based Phylogeography -- How to Infer Ancestral Genome Features by Parsimony -- Duplication, Rearrangement and Reconciliation -- The Genesis of the DCJ Formula -- Part II: New Lights on Current Paradigms -- Large-Scale Multiple Sequence Alignment and Phylogeny Estimation -- Rearrangements in Phylogenetic Inference -- Status of Research on Insertion and Deletion Variations in the Human Population -- A Retrospective on Genomic Preprocessing for Comparative Genomics -- A Comparison of DCJ and Algebraic Distances -- Part III: Promising Directions -- Fractionation, Rearrangement, Consolidation, Reconstruction -- Error Detection and Correction of Gene Trees -- The Potential of Family-Free Genome Comparison -- Genetic History of Populations.
520 _aThis authoritative text/reference presents a review of the history, current status, and potential future directions of computational biology in molecular evolution. Gathering together the unique insights of an international selection of prestigious researchers, this must-read volume examines the latest developments in the field, the challenges that remain, and the new avenues emerging from the growing influx of sequence data. These viewpoints build upon the pioneering work of David Sankoff, one of the founding fathers of computational biology, and mark the 50th anniversary of his first scientific article. Topics and features: Discusses the development of the BLAST algorithm, model-based phylogeography techniques, and the double cut and join (DCJ) distance formula Reviews the reconstruction of evolutionary features of ancestral genomes in a known phylogeny, and presents integrative models of evolution Introduces algorithms to estimate alignment and phylogeny on ultra-large datasets, and an approach for using likelihood methods with rearrangement models Examines the impact of insertion and deletion variants in human biology, evolution and health Surveys novel and recent research on genomic distance and family-free genome comparison Describes consolidation methods for reconstruction of ancestral gene orders, and error detection in gene tree construction Investigates  the genetic events recoverable from simulations of human population histories The broad spectrum of rich contributions in this essential collection will appeal to all computer scientists, mathematicians and biologists involved in comparative genomics, phylogenetics and related areas.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700 1 _aEl-Mabrouk, Nadia.
_eeditor.
_9315006
700 1 _aTannier, Eric.
_eeditor.
_9315007
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9781447152972
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-1-4471-5298-9
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c286404
_d286404