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008			150903s2011 xxu| o |||| 0|eng d
020			_a9781461404781 _99781461404781
024	7		_a10.1007/9781461404781 _2doi
035			_avtls000340307
039		9	_a201509030843 _bVLOAD _c201404300413 _dVLOAD _y201402061022 _zstaff
040			_aMX-SnUAN _bspa _cMX-SnUAN _erda
050		4	_aQA273.A1-274.9
100	1		_aUllah, Mukhtar. _eautor _9315608
245	1	0	_aStochastic Approaches for Systems Biology / _cby Mukhtar Ullah, Olaf Wolkenhauer.
264		1	_aNew York, NY : _bSpringer New York, _c2011.
300			_axxxii, 290 páginas 73 ilustraciones _brecurso en línea.
336			_atexto _btxt _2rdacontent
337			_acomputadora _bc _2rdamedia
338			_arecurso en línea _bcr _2rdacarrier
347			_aarchivo de texto _bPDF _2rda
500			_aSpringer eBooks
505	0		_aPreface.-  Acknowledgements -- Acronyms, notation -- Matlab functions, revisited examples -- Introduction -- Biochemical reaction networks -- Randomness -- Probability and random variables -- Stochastic modeling of biochemical networks -- The 2MA approach -- The 2MA cell cycle model -- Hybrid Markov processes -- Wet-lab experiments and noise -- Glossary.
520			_aThis textbook focuses on stochastic modelling and its applications in systems biology. In addition to a review of probability theory, the authors introduce key concepts, including those of stochastic process, Markov property, and transition probability, side by side with notions of biochemical reaction networks. This leads to an intuitive presentation guided by a series of biological examples that are revisited throughout the text. The text shows how the notion of propensity, the chemical master equation and the stochastic simulation algorithm arise as consequences of the Markov property. The nontrivial relationships between various stochastic approaches are derived and illustrated. The text contains many illustrations, examples and exercises to communicate methods and analyses. Matlab code to simulate cellular systems is also provided where appropriate and the reader is encouraged to experiment with the examples and case studies provided. Senior undergraduate and graduate students in applied mathematics, the engineering and physical sciences as well as researchers working in the areas of systems biology, theoretical and computational biology will find this text useful.
590			_aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700	1		_aWolkenhauer, Olaf. _eautor _9315609
710	2		_aSpringerLink (Servicio en línea) _9299170
776	0	8	_iEdición impresa: _z9781461404774
856	4	0	_uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-1-4614-0478-1 _zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
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999			_c286761 _d286761