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008 150903s2012 xxu| o |||| 0|eng d
020 _a9781461409809
_99781461409809
024 7 _a10.1007/9781461409809
_2doi
035 _avtls000340455
039 9 _a201509030844
_bVLOAD
_c201404300415
_dVLOAD
_y201402061025
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aQR355-502
100 1 _aRossmann, Michael G.
_eeditor.
_9315835
245 1 0 _aViral Molecular Machines /
_cedited by Michael G. Rossmann, Venigalla B. Rao.
264 1 _aBoston, MA :
_bSpringer US,
_c2012.
300 _axiv, 687 páginas 221 ilustraciones, 192 ilustraciones en color.
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v726
500 _aSpringer eBooks
505 0 _aViruses: Sophistiated Biological Machines -- F1-Atpase: A Prototypical Molecular Motor -- Reconstructing Virus Structures From Nanometer To Near-Atomic Resolutions With Cryo-Electron Microscropy And Tomography -- Principles Of Virus Structural Organization -- Viral Entry Machines -- Genome Replication Machines -- Capsid Assembly And Maturation -- Genome Packaging Machines.
520 _aA biological organism can be viewed as a collection of molecular machines well integrated to function as a self-replicating unit. One of the principal goals in biology is to be able to fully understand the mechanisms of an organism in atomic detail. Viruses offer the best opportunities to achieve this goal. Written by leaders in the respective fields, this book examines a variety of viral molecular machines, using the best examples from bacteriophages and animal viruses, many causing infectious diseases of public health importance. Beginning with the viral entry into a host cell, the book takes the reader through replication of the genome, assembly of structural components, genome packaging and maturation into an infectious virion. The book conveys the state of the art knowledge of the topic generated by combining X-ray crystallography, high resolution electron microscopy, molecular genetics, biochemistry, and single molecule biophysics. Viral Molecular Machines is not only a “must-have” book for virologists but it will also be broadly useful for molecular biologists in academia and industry as well as an educational tool for teaching graduate and upper level undergraduate students.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700 1 _aRao, Venigalla B.
_eeditor.
_9315836
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9781461409793
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-1-4614-0980-9
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c286900
_d286900