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001			288729
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007			cr nn 008mamaa
008			150903s2012 xxu| o |||| 0|eng d
020			_a9781461416807 _99781461416807
024	7		_a10.1007/9781461416807 _2doi
035			_avtls000340657
039		9	_a201509030349 _bVLOAD _c201404300418 _dVLOAD _y201402061031 _zstaff
040			_aMX-SnUAN _bspa _cMX-SnUAN _erda
050		4	_aQR180-189.5
100	1		_aLópez-Larrea, Carlos. _eeditor. _9314393
245	1	0	_aSelf and Nonself / _cedited by Carlos López-Larrea.
264		1	_aNew York, NY : _bSpringer US, _c2012.
300			_axxii, 318 páginas 35 ilustraciones, 22 ilustraciones en color. _brecurso en línea.
336			_atexto _btxt _2rdacontent
337			_acomputadora _bc _2rdamedia
338			_arecurso en línea _bcr _2rdacarrier
347			_aarchivo de texto _bPDF _2rda
490	0		_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v738
500			_aSpringer eBooks
505	0		_aThe Origin of the Bacterial Immune Response -- The Evolution of Self During the Transition to Multicellularity -- Glyconectin Glycans as the Self-Assembling Nano-Molecular-Velcrosystem Mediating Self-Nonself Recognition and Adhesion Implicated in Evolution of Multicellularity -- Neglected Biological Features in Cnidarians Self-Nonself Recognition -- Intracellular Inflammatory Sensors For Foreign Invaders and Substances of Self-Origin -- Nonself Perception in Plant Innate Immunity -- How Did Flowering Plants Learn to Avoid Blind Date Mistakes? Self?Incompatibility in Plants and Comparisons with Nonself Rejection in the Immune Response -- Signaling Pathways that Regulate Life and Cell Death: Evolution of Apoptosis in the Context of Self?Defense -- Sensing Necrotic Cells -- Sensing Endoplasmic Reticulum Stress -- Autophagy and Self-Defense -- Viruses and Host Evolution: Virus?Mediated Self Identity -- The Evolution of Adaptive Immunity -- Epigenetic Code and Self-Identity -- Viral Immunomodulatory Proteins: Usurping Host Genes as a Survival Strategy -- The Emergence of the Major Histocompatilibility Complex -- MHC Signaling During Social Communication.
520			_aIn 1960 Sir Frank Macfarlane Burnet received the Noble Prize in Physiology and Medicine. He titled his Nobel Lecture “Immunological Recognition of Self” emphasizing the central argument of immunological tolerance in “How does the vertebrate organism recognize self from nonself in this the immunological sense—and how did the capacity evolve.” The concept of self is linked to the concept of biological self identity. All organisms, from bacteria to higher animals, possess recognition systems to defend themselves from nonself. Even in the context of the limited number of metazoan phyla that have been studied in detail, we can now describe many of the alternative mechanism of immune recognition that have emerged at varying points in phylogeny. Two different arms—the innate and adaptive immune system—have emerged at different moments in evolution, and they are conceptually different. The ultimate goals of immune biology include reconstructing the molecular networks underlying immune processes.
590			_aPara consulta fuera de la UANL se requiere clave de acceso remoto.
710	2		_aSpringerLink (Servicio en línea) _9299170
776	0	8	_iEdición impresa: _z9781461416791
856	4	0	_uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-1-4614-1680-7 _zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
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999			_c288729 _d288729