000 03604nam a22003855i 4500
001 289584
003 MX-SnUAN
005 20160429154715.0
007 cr nn 008mamaa
008 150903s2005 xxu| o |||| 0|eng d
020 _a9781592599172
_99781592599172
024 7 _a10.1007/9781592599172
_2doi
035 _avtls000342859
039 9 _a201509030859
_bVLOAD
_c201405050248
_dVLOAD
_y201402061137
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aRC681-688.2
100 1 _aQuinn, Martin.
_eeditor.
_9319870
245 1 0 _aPlatelet Function :
_bAssessment, Diagnosis, and Treatment /
_cedited by Martin Quinn, Desmond Fitzgerald.
264 1 _aTotowa, NJ :
_bHumana Press,
_c2005.
300 _axI, 397 páginas
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aContemporary Cardiology
500 _aSpringer eBooks
505 0 _aPlatelet Physiology -- Platelet Physiology -- Platelet Integrins and Signaling -- Platelet Adhesion -- Structure-Function of the Platelet Cytoskeleton -- Platelets and Inflammation -- Platelet Signal-Dependent Protein Synthesis -- Phosphoproteomics of Human Platelets -- Assessing Platelet Function -- Platelet Function Studies -- Platelet Function Under Flow -- Pharmacodynamics of GPIIb-IIIa Receptor Blockade -- Prostanoid Generation in Platelet Function -- Platelets and Prothrombin -- Markers of Platelet Activation and Granule Secretion -- Genomic and Proteomic Analysis of Platelets -- Clinical Applications -- Antiplatelet Agents -- Assessing Platelet Function in Clinical Trials.
520 _aPlatelet function, or clot formation, is difficult to assess, but extremely important because inadvertent or excessive platelet activation underlies many common cardiovascular disorders, such as myocardial infarction, unstable angina, and stroke. In Platelet Function: Assessment, Diagnosis, and Treatment, a panel of leading researchers and clinicians review the latest findings on the complexities of platelet function and the various means of inhibiting platelet clot formation. The authors delineate an up-to-date picture of platelet biology and describe methods for assessing platelet function, including the commonly used platelet aggregation, thromboxane production, procoagulant function, platelet function under flow, and the expression of platelet activation markers. The focus is both on the technology and the outcome of research on platelets, including the fast developing fields of proteomics and genomics and their application to platelet research. The clinical applications of the various methods for the assessment of platelet function in vivo, as well as antiplatelet therapy, are fully discussed. Comprehensive and state of the art, Platelet Function: Assessment, Diagnosis, and Treatment offers vascular researchers and clinicians a sound foundation for understanding platelet biology, assessing thrombotic risk in patients, and determining the rational dosing of antiplatelet agents.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700 1 _aFitzgerald, Desmond.
_eeditor.
_9319871
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9781588292445
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-1-59259-917-2
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c289584
_d289584