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001			289589
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007			cr nn 008mamaa
008			150903s2006 xxu| o |||| 0|eng d
020			_a9781592599943 _99781592599943
024	7		_a10.1007/9781592599943 _2doi
035			_avtls000342905
039		9	_a201509030859 _bVLOAD _c201405050249 _dVLOAD _y201402061143 _zstaff
040			_aMX-SnUAN _bspa _cMX-SnUAN _erda
050		4	_aRC254-282
100	1		_aHearing, Vincent J. _eeditor. _9319877
245	1	0	_aFrom Melanocytes to Melanoma : _bThe Progression to Malignancy / _cedited by Vincent J. Hearing, Stanley P. L. Leong.
264		1	_aTotowa, NJ : _bHumana Press, _c2006.
300			_brecurso en línea.
336			_atexto _btxt _2rdacontent
337			_acomputadora _bc _2rdamedia
338			_arecurso en línea _bcr _2rdacarrier
347			_aarchivo de texto _bPDF _2rda
500			_aSpringer eBooks
505	0		_aMelanocyte Development and Function -- The Origin and Development of Neural Crest-Derived Melanocytes -- MITF -- MITF -- Melanocytes and the Transcription Factor Sox10 -- Human Cutaneous Pigmentation -- Melanocyte Distribution and Function in Human Skin -- Melanocyte Transformation and Progression to Melanoma -- Altered Signal Transduction in Melanoma -- BRN2 in Melanocytic Cell Development, Differentiation, and Transformation -- The Dynamic Roles of Cell-Surface Receptors in Melanoma Development -- Familial Melanoma Genes, Melanocyte Immortalization, and Melanoma Initiation -- Genetic Progression From Melanocyte to Malignant Melanoma -- The Multiple Roles of the Oncogenic Protein SKI in Human Malignant Melanoma -- RB/E2F Regulation and Dual Activity in the Melanocytic System -- Melanoma Development and Pigment Cell Transformation -- The Biology and Genetics of Melanoma -- The Biology of Xeroderma Pigmentosum -- Divergent Pathways to Cutaneous Melanoma -- Pigmentation, DNA Repair, and Candidate Genes -- Low-Penetrance Genotypes, Pigmentation Phenotypes, and Melanoma Etiology -- The Biology of Melanoma Progression -- Optical Imaging Analysis of Atypical Nevi and Melanoma -- Proteomics Analysis of Melanoma Cell Lines and Cultured Melanocytes -- Primary Invasive Melanoma to Metastatic Melanoma -- Paradigm of Metastasis for Malignant Melanoma -- Repair of UV-Induced DNA Damage and Melanoma Risk -- High-Risk Factors for Melanoma Metastasis -- Role of Melanoma Inhibitory Activity in Early Development of Malignant Melanoma -- Role and Regulation of PAR-1 in Melanoma Progression -- Molecular Mechanisms of Melanoma Metastasis -- Overview of Tumor Progression in Melanoma -- The Plasticity of Melanoma Cells and Associated Clinical Implications -- The Clinical Use of Molecular Markers as Predictors of Disease Outcome and Response to Therapy in Malignant Melanoma -- The Role of DCT/TYRP2 in Resistance of Melanoma Cells to Drugs and Radiation -- How Melanoma Cells Evade Chemotherapy -- Apoptosis in Melanoma -- Role of Melanoma-Associated Antigens -- Host Responses to Melanoma -- Future Perspectives.
520			_aMelanoma offers an excellent model for cancer biology and an opportunity to understand the progression of a normal skin cell-the melanocyte-to malignancy. In From Melanocytes to Melanoma: The Progression to Malignancy, leading researchers and clinicians join forces to explain how skin cancer develops from its benign precursor cell type. The authors focus on the molecular mechanisms involved in melanogenesis, the malignant transformation of melanocytes, and the further progression of primary melanomas into invasive and metastatic melanomas. They also review recent advances in our understanding of the basic biology of melanocytes and the development, migration, and differentiation of melanoblasts into melanocytes. The text is augmented by four color plates. Comprehensive and illuminating, From Melanocytes to Melanoma: The Progression to Malignancy, provides pathologists, dermatologists, surgeons, and medical oncologists with an up-to-date understanding of the progressive mechanisms of oncological development in malignant melanoma, a likely model of malignant progress for other types of cancer, and the ongoing development of novel therapeutics.
590			_aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700	1		_aLeong, Stanley P. L. _eeditor. _9299719
710	2		_aSpringerLink (Servicio en línea) _9299170
776	0	8	_iEdición impresa: _z9781588294593
856	4	0	_uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-1-59259-994-3 _zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
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