000			04588nam a22003975i 4500
001			290863
003			MX-SnUAN
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007			cr nn 008mamaa
008			150903s2009 xxk| o |||| 0|eng d
020			_a9781848002555 _99781848002555
024	7		_a10.1007/9781848002555 _2doi
035			_avtls000344239
039		9	_a201509030405 _bVLOAD _c201405050304 _dVLOAD _y201402061251 _zstaff
040			_aMX-SnUAN _bspa _cMX-SnUAN _erda
050		4	_aQH324.2-324.25
100	1		_aUssery, David W. _eeditor. _9321837
245	1	0	_aComputing for Comparative Microbial Genomics : _bBioinformatics for Microbiologists / _cedited by David W. Ussery, Trudy M. Wassenaar, Stefano Borini.
264		1	_aLondon : _bSpringer London, _c2009.
300			_brecurso en línea.
336			_atexto _btxt _2rdacontent
337			_acomputadora _bc _2rdamedia
338			_arecurso en línea _bcr _2rdacarrier
347			_aarchivo de texto _bPDF _2rda
490	0		_aComputational Biology, _x1568-2684 ; _v8
500			_aSpringer eBooks
505	0		_aIntroductions -- Sequences as Biological Information: Cells Obey the Laws of Chemistry and Physics -- Bioinformatics for Microbiologists: An Introduction -- Microbial Genome Sequences: A New Era in Microbiology -- An Overview of Genome Databases -- The Challenges of Programming: A Brief Introduction -- Comparative Genomics -- Methods to Compare Genomes The First Examples -- Genomic Properties: Length, Base Composition and DNA Structures -- Word Frequencies and Repeats -- Transcriptomics and Proteomics -- Transcriptomics: Translated and Untranslated RNA -- Expression of Genes and Proteins -- Of Proteins, Genomes, and Proteomes -- Microbial Communities -- Microbial Communities: Core and Pan-Genomics -- Metagenomics of Microbial Communities -- Evolution of Microbial Communities; or, On the Origins of Bacterial Species.
520			_aThe major difficulty many microbiologists face is simply that of too much information. As a result of sequencing technologies becoming so economical, there is a very real and pressing need for high-throughput computational methods to compare hundreds and thousands of bacterial genomes. This accessible text/reference provides a coherent set of tools and a methodological framework for comparing raw DNA sequences and fully annotated genome sequences, then using these to build up and test models about groups of interacting organisms within an environment or ecological niche. Easy-to-follow, this introductory textbook is built around teaching computational / bioinformatics methods for comparison of microbial genomes, and includes detailed examples of how to compare them at the level of DNA, RNA, and protein, in terms of structural and functional analysis. Topics and Features: • Contains five introductory chapters each representing a specific scientific field, to bring all readers up to the same basic level • Familiarizes readers with genome sequences, RNA sequences (transcriptomics), proteomics and regulation of gene expression • Describes basic methods to compare genomes and visualize the results for easy interpretation • Discusses microbial communities, providing a framework for analysing and comparing individual genomes or raw DNA derived from complete ecosystems • Introduces various atlases, building up to the Genome Atlas • Offers numerous helpful examples throughout • Focuses on the use and interpretation of publicly available Web tools • Provides supplemental resources, such as Web links, at http://comparativemicrobial.com Developed from a set of lectures for a course in Comparative Microbial Genomics taught since 2001, this wide-ranging foundational textbook is aimed at advanced undergraduate and graduate students in Bioinformatics and Microbiology. The authors are from diverse backgrounds complementing the interdisciplinary nature of the topic and consequently have developed a common scientific language. Readers will find this text an invaluable reference for computational and bioinformatics tools.
590			_aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700	1		_aWassenaar, Trudy M. _eeditor. _9321838
700	1		_aBorini, Stefano. _eeditor. _9321839
710	2		_aSpringerLink (Servicio en línea) _9299170
776	0	8	_iEdición impresa: _z9781848002548
856	4	0	_uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-1-84800-255-5 _zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
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999			_c290863 _d290863