000 03260nam a22003855i 4500
001 291265
003 MX-SnUAN
005 20170705134223.0
007 cr nn 008mamaa
008 150903s2011 xxk| o |||| 0|eng d
020 _a9781848826441
_99781848826441
024 7 _a10.1007/9781848826441
_2doi
035 _avtls000344498
039 9 _a201509030408
_bVLOAD
_c201405050308
_dVLOAD
_y201402061258
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aRB155-155.8
100 1 _aRoach, Helmtrud I.
_eeditor.
_9316251
245 1 0 _aEpigenetic Aspects of Chronic Diseases /
_cedited by Helmtrud I. Roach, Felix Bronner, Richard O.C. Oreffo.
264 1 _aLondon :
_bSpringer London :
_bImprint: Springer,
_c2011.
300 _axviii, 238 páginas 48 ilustraciones, 42 ilustraciones en color.
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
500 _aSpringer eBooks
505 0 _aEpigenetics and Chronic Diseases: An Overview -- Techniques to Study DNA Methylation and Histone Modification -- Mechanisms of Epigenetic Gene Silencing -- Mechanisms of Epigenetic Gene Activation in Disease: Dynamics of DNA Methylation and Demethylation -- The Role of Histone Demethylases in Disease -- Autoimmune Diseases -- Epigenetics of Rheumatoid Arthritis -- DNA Methylation Changes in Osteoarthritis -- Epigenetics and Type 2 Diabetes -- Epigenetic Regulation of Asthma and Allergic Diseases -- Epigenetics in Psychiatry -- Epigenetics and Late-Onset Alzheimer’s Disease -- Epigenetic Mechanisms in the Developmental Origins of Adult Disease -- Targeting Histone Deacetylases in Chronic Obstructive Pulmonary Disease -- Clinical Trials of Epigenetic Modifiers in the Treatment of Myelodysplastic Syndrome.
520 _aEpigenetic Aspects of Chronic Diseases assembles in comprehensive form what is known about the role of epigenetics in chronic disease development. This book provides new insights into treatment, including modulation of epigenetic regulation. Each chapter gives an outline of a respective disease, explains why epigenetics may be involved in the disease process and then presents the evidence of how changes in epigenetic status contribute to initiation and progress of the disease. The final chapters look towards future therapeutic treatment, based on manipulation of epigenetic aspects. Written by widely published experts, Epigenetic Aspects of Chronic Diseases is a valuable reference tool for clinicians and researchers who investigate and treat chronic diseases, as well as health care personnel, post-doctoral fellows and medical or dental students.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700 1 _aBronner, Felix.
_eeditor.
_9316249
700 1 _aOreffo, Richard O.C.
_eeditor.
_9322473
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9781848826434
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-1-84882-644-1
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c291265
_d291265