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008 150903s2012 sz | o |||| 0|eng d
020 _a9783034602198
_99783034602198
024 7 _a10.1007/9783034602198
_2doi
035 _avtls000345191
039 9 _a201509030410
_bVLOAD
_c201405050317
_dVLOAD
_y201402061330
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aR-RZ
100 1 _aThiel, Andreas.
_eeditor.
_9324833
245 1 0 _aImmunosenescence /
_cedited by Andreas Thiel.
264 1 _aBasel :
_bSpringer Basel :
_bImprint: Springer,
_c2012.
300 _axviii, 235 páginas 4 ilustraciones, 2 ilustraciones en color.
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aBirkhäuser Advances in Infectious Diseases
500 _aSpringer eBooks
505 0 _aRegulation of Adaptive Immunity in the Elderly -- Does Innate Immunity Get Old? -- Thy(-Im)Munosenescence: The Ageing of the Thymus and Its Impact on the Immune System -- Characteristics of B Cells and B Cell Responses in Aged Individuals -- Mechanisms of Immune Protection to Pneumococcal Infection in the Young and the Elderly -- CMV Subversion of the Immune System in Later Life -- Aging and Autoimmunity -- Vaccination in the Elderly -- Immunosenescence and the 3r’s; Restoration, Replacement and Reprogramming -- Novel Strategies of Improved Vaccines for Elderly: The Example of Influenza.
520 _aAs individuals age, their ability to respond to and clear pathogens and to control unwanted immune reactions declines, leading to a greater incidence of certain infectious diseases, autoimmunity and general immune dysfunctions. Most remarkably, the efficacy of vaccines is frequently decreased in elderly persons. Therefore, age-associated dysfunctions of the humoral and cellular immune responses have a strong clinical impact. Improving our understanding of the aged immune system is crucial in developing effective prevention and treatment programs that will facilitate healthy aging and improve the quality of life of the elderly population. The aim of this volume is to summarize current knowledge on the cellular and molecular aspects of the aging immune system, with an emphasis on infectious diseases and new therapeutic approaches.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9783034602181
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-3-0346-0219-8
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c292774
_d292774