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008 150903s2012 sz | o |||| 0|eng d
020 _a9783034802185
_99783034802185
024 7 _a10.1007/9783034802185
_2doi
035 _avtls000345277
039 9 _a201509030346
_bVLOAD
_c201405050318
_dVLOAD
_y201402061332
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aRM1-950
100 1 _aMolineux, Graham.
_eeditor.
_9325140
245 1 0 _aTwenty Years of G-CSF :
_bClinical and Nonclinical Discoveries /
_cedited by Graham Molineux, MaryAnn Foote, Tara Arvedson.
264 1 _aBasel :
_bSpringer Basel,
_c2012.
300 _axxii, 471 páginas 54 ilustraciones, 4 ilustraciones en color.
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aMilestones in Drug Therapy
500 _aSpringer eBooks
505 0 _aBasic Science -- Use of rHuG-CSF in the Oncology Setting -- Use of rHuG-CSF in Non-Oncology Setting -- Safety and Economics -- The Next 20 Years.
520 _aGranulocyte colony-stimulating factor (G-CSF or GCSF) is a secreted glycoprotein that stimulates the proliferation and differentiation of granulocyte precursor cells, and induces mobilization of peripheral blood progenitor cells from the bone marrow. Development of recombinant human G-CSF has had a profound impact on the treatment of many diseases, including severe chronic neutropenia and cancer, and has enabled peripheral stem cell transplantation to supplant bone marrow transplantation in the autologous setting. This Milestones in Drug Therapy volume describes the experience of the last 20 years of treatment with recombinant human G-CSF, including the basic science, the use of recombinant human G-CSF in both the oncology and nononcology settings, and the safety and economics of its use. Many of the authors were the original investigators of recombinant human G-CSF and other authors are key researchers who provide their outlook for the next 20 years for use of and research with recombinant human G-CSF.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700 1 _aFoote, MaryAnn.
_eeditor.
_9325141
700 1 _aArvedson, Tara.
_eeditor.
_9325142
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9783034802178
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-3-0348-0218-5
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c292946
_d292946