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020 _a9783540269403
_99783540269403
024 7 _a10.1007/b138340
_2doi
035 _avtls000346777
039 9 _a201509031100
_bVLOAD
_c201405070511
_dVLOAD
_y201402070905
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aRC648-665.2
100 1 _aKordon, Claude.
_eeditor.
_9326897
245 1 0 _aHormones and the Brain /
_cedited by Claude Kordon, Rolf-Christian Gaillard, Yves Christen.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2005.
300 _axvii, 238 páginas 53 ilustraciones
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aResearch and Perspectives in Endocrine Interactions
500 _aSpringer eBooks
505 0 _aActivins and inhibins: Physiological roles, signaling mechanisms and regulation -- Twins and the fetal origins hypothesis: An application to growth data -- Towards Understanding the Neurobiology of Mammalian Puberty: Genetic, Genomic and Proteomic Approaches -- The non-genomic Action of Sex Steroids -- Mechanisms of Steroid Hormone Actions on Hypothalamic Nerve Cells: Molecular and Biophysical Studies relevant for Hormone-dependent Behaviors -- Biological Effects and Markers of Exposure to Xenosteroids and Selective Estrogen Receptor Modulators (SERMs) at the Hypothalamic-Pituitary Unit -- Regulation of Neurosteroid Biosynthesis by Neurotransmitters and Neuropeptides -- Progestins and antiprogestins: mechanisms of action, neuroprotection and myelination -- Rapid Effects of Estradiol on Motivated Behaviors -- Behavioral Effects of rapid Changes in Aromatase Activity in the Central Nervous System -- Modulators of Endogenous Neuroprotection: Estrogen, Corticotropin-releasing Hormone and Endocannabinoids -- Estrogens, Aging, and Neurodegenerative Diseases -- Hormones, Stress and Depression.
520 _aPeripheral hormones have a major impact on the brain: they are able to interfere with its development, to affect release of neurotransmitters and concentrations of receptors, to trigger growth factors involved in lesion repair. These multiple actions account for their capacity to modulate a number of physiological parameters, from reproductive functions to memory, behaviour and aging. Depending upon intensity and duration of exposure, they can be either neuroprotective or neurotoxic, for instance by affecting production of free radicals. This book, based on contributions of pioneer investigators in the field, outlines the ambiguous actions of gonadal steroids (estradiol, progesterone, testosterone, inhibin and activin) and of neurosteroids, related moieties produced in the brain itself. After summarizing their multiple mechanisms of action, which involve both direct effects on neuronal membranes and activation of genes coding for specific proteins in neurons or glial cells, the book outlines the role of hormones in pathogenic processes such as mental disturbances or neurodegenerative diseases.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700 1 _aGaillard, Rolf-Christian.
_eeditor.
_9326898
700 1 _aChristen, Yves.
_eeditor.
_9326128
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9783540213550
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/b138340
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c293867
_d293867