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001 293897
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008 150903s2005 gw | o |||| 0|eng d
020 _a9783540266167
_99783540266167
024 7 _a10.1007/b137762
_2doi
035 _avtls000346665
039 9 _a201509031115
_bVLOAD
_c201405070508
_dVLOAD
_y201402070902
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aRC254-282
100 1 _aCheung, Nai-Kong V.
_eeditor.
_9326964
245 1 0 _aNeuroblastoma /
_cedited by Nai-Kong V. Cheung, Susan L. Cohn.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2005.
300 _axv, 300 páginas 51 ilustraciones
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aPediatric Oncology,
_x1613-5318
500 _aSpringer eBooks
505 0 _aEpidemiology -- Screening for Neuroblastoma -- Genetics -- Molecular Cytogenetics -- Molecular and Developmental Biology of Neuroblastoma -- Cellular Heterogeneity -- Clinical Presentation -- Pathology of Peripheral Neuroblastic Tumors -- Molecular Pathology of Neuroblastic Tumors Based on Genome-wide Expression Analysis -- Anatomic and Functional Imaging -- Treatment of Neuroblastoma -- Treatment of Relapsed and Refractory Neuroblastoma -- Management of Neurologic Complications -- Immunology and Immunotherapy -- Differentiation and Retinoids -- Angiogenesis -- Experimental Therapeutics and Preclinical Models -- Late Effects of Treatment -- Perspectives and Future Directions.
520 _aNeuroblastoma is a medical enigma. As a childhood neoplasm arising from neural crest cells, it is characterized by diverse clinical behaviors ranging from spontaneous remission to rapid tumor progression and death. Although clinical outcome can be predicted to a large extent by the stage of disease and the age at diagnosis, an in-depth understanding of its clinico-pathological behavior, now greatly aided by sophisticated molecular genetic profiling, will improve diagnostic precision and refine risk-based therapies. Comprehensive international efforts have advanced our understanding of tumor biology and improved the clinical management of children with neuroblastoma. This book reviews our current understanding of the genes and biological pathways that contribute to neuroblastoma pathogenesis, modern risk-based treatment approaches for these patients, and recent advances in biologically based therapy. It provides a concise up-to-date reference for practitioners, students, and researchers.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700 1 _aCohn, Susan L.
_eeditor.
_9326965
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9783540408413
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/b137762
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c293897
_d293897