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020 _a9783540314547
_99783540314547
024 7 _a10.1007/b95147
_2doi
035 _avtls000347685
039 9 _a201509030440
_bVLOAD
_c201405070517
_dVLOAD
_y201402070937
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aQH573-671
100 1 _aGrosjean, Henri.
_eeditor.
_9329450
245 1 0 _aFine-Tuning of RNA Functions by Modification and Editing /
_cedited by Henri Grosjean.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2005.
300 _axxiv, 442 páginas 79 ilustraciones, 14 en color. Also available online.
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aTopics in Current Genetics,
_x1610-2096 ;
_v12
500 _aSpringer eBooks
505 0 _aModification and Editing of RNA: an Overview -- Biosynthesis and Function of tRNA Wobble Modifications -- Editing and Modification in Trypanosomes : the Reshaping of Non-coding RNAs -- Transfer RNA Modification and Modifying Enzymes in Yeast -- Biosynthesis and Function of 1-methyladenosine in Transfer RNA -- The Biosynthesis and Functional Roles of Methylated Nucleosides in Eukaryotic mRNA -- Role of the 5’-cap in the Biosynthesis of Splicesomal snRNPs -- Role of a Conserved Pseudouridine on the Structural and Electrostatic Features of the Splicesomal Pre-mRNA Branch Site -- RNA-guided RNA Modification -- Conserved Ribosomal RNA Modification and Their Putative Roles in Ribosome Biogenesis and Translation -- Nucleotide Methylations in rRNA that Confer Resistance to Ribosome-targeting Antibiotics -- Translational Recoding and RNA Modifications -- Adenosine to Inosine RNA Editing in Animal Cells -- Mammalian C-to-U Editing -- Transfer RNA Modifications and DNA Editing in HIV-1 Reverse Transcription -- Methylation of Selenocysteine tRNA Governs Differential Expression of Mammalian Selenoproteins.
520 _aNaturally occurring RNA always contains numerous biochemically altered nucleotides. They are formed by enzymatic modification of the primary transcripts during the complex RNA maturation process designated RNA modification. A large number of enzymes catalyzing the formation of these modified nucleosides or converting one canonical base into another at the posttranscriptional level have been studied for many years, but only recently have systematic and comparative studies begun. The functions of individual enzymes and/or the modified/edited nucleosides in RNA, however, have remained largely ignored. This book provides advance information on RNA modification, including the associated editing machinery, while offering the reader some perspective on the significance of such modifications in fine-tuning the structure and functions of mature RNA molecules and hence the ability to influence the efficiency and accuracy of genetic expression. Outstanding scientists who are actively working on RNA modification/editing processes have provided up-to-date information on these intriguing cellular processes that have been generated over the course of millions of years in all living organisms. Each review has been written and illustrated for a large audience of readers, not only specialists in the field, but also for advanced students or researchers who want to learn more about recent progress in RNA modification and editing.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9783540244950
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/b95147
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c295215
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