000 02800nam a22004095i 4500
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020 _a9783540313397
_99783540313397
024 7 _a10.1007/9783540313397
_2doi
035 _avtls000347653
039 9 _a201509030919
_bVLOAD
_c201405050339
_dVLOAD
_y201402070936
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aRC261-271
100 1 _aBringmann, P.
_eeditor.
_9329773
245 1 0 _aSystems Biology :
_bApplications and Perspectives /
_cedited by P. Bringmann, E. C. Butcher, G. Parry, B. Weiss.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2007.
300 _axiii, 172 páginas 40 ilustraciones
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aErnst Schering Research Foundation Workshop,
_x0947-6075 ;
_v61
500 _aSpringer eBooks
505 0 _aRNAi Applications in Target Validation -- Does the Serum Peptidome Reveal Hemostatic Dysregulation? -- Systems Biology: New Paradigms for Cell Biology and Drug Design -- The Theory of Biological Robustness and Its Implication in Cancer -- Network Genomics -- A Plea for More Theory in Molecular Biology -- Applying a Causal Framework to System Modeling -- Can Cell Systems Biology Rescue Drug Discovery?.
520 _aThis volume features contributions from participants of an ESRF Workshop on "Systems Biology" held in Berkeley, USA, in November 2005. Significant progress has been made in developing technologies that enable systems interrogations at a molecular level. Overwhelming data sets are generated ever faster, providing enormous detail. In order to be useful, however, all these data must be appropriately integrated, analyzed in the context of all other information available and eventually modelled, enabling predictions for therapeutic interventions. Recent successes and challenges of applying systems level measurements to the different steps of drug discovery and development in the pharmaceutical industry are summarized.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700 1 _aButcher, E. C.
_eeditor.
_9329774
700 1 _aParry, G.
_eeditor.
_9329775
700 1 _aWeiss, B.
_eeditor.
_9329776
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9783540313380
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-3-540-31339-7
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c295387
_d295387