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020 _a9783540353065
_99783540353065
024 7 _a10.1007/9783540353065
_2doi
035 _avtls000349059
039 9 _a201509030413
_bVLOAD
_c201405050342
_dVLOAD
_y201402071153
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aQH505
100 1 _aBastolla, Ugo.
_eeditor.
_9330065
245 1 0 _aStructural Approaches to Sequence Evolution :
_bMolecules, Networks, Populations /
_cedited by Ugo Bastolla, Markus Porto, H. Eduardo Roman, Michele Vendruscolo.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2007.
300 _axIx, 367 páginas 95 ilustraciones, 1 en color.
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aBiological and Medical Physics, Biomedical Engineering,
_x1618-7210
500 _aSpringer eBooks
505 0 _aMolecules: Proteins and RNA -- Modeling Conformational Flexibility and Evolution of Structure: RNA as an Example -- Gene3D and Understanding Proteome Evolution -- The Evolution of the Globins: We Thought We Understood It -- The Structurally Constrained Neutral Model of Protein Evolution -- Towards Unifying Protein Evolution Theory -- Molecules: Genomes -- A Twenty-First Century View of Evolution: Genome System Architecture, Repetitive DNA, and Natural Genetic Engineering -- Genomic Changes in Bacteria: From Free-Living to Endosymbiotic Life -- Phylogenetic Analysis -- Molecular Phylogenetics: Mathematical Framework and Unsolved Problems -- Phylogenetics and Computational Biology of Multigene Families -- SeqinR 1.0-2: A Contributed Package to the R Project for Statistical Computing Devoted to Biological Sequences Retrieval and Analysis -- Networks -- Evolutionary Genomics of Gene Expression -- From Biophysics to Evolutionary Genetics: Statistical Aspects of Gene Regulation -- Populations -- Drift and Selection in Evolving Interacting Systems -- Adaptation in Simple and Complex Fitness Landscapes -- Genetic Variability in RNA Viruses: Consequences in Epidemiology and in the Development of New Stratgies for the Extinction of Infectivity.
520 _aStructural requirements constrain the evolution of biological entities at all levels, from macromolecules to their networks, right up to populations of biological organisms. Classical models of molecular evolution, however, are focused at the level of the symbols - the biological sequence - rather than that of their resulting structure. Now recent advances in understanding the thermodynamics of macromolecules, the topological properties of gene networks, the organization and mutation capabilities of genomes, and the structure of populations make it possible to incorporate these key elements into a broader and deeply interdisciplinary view of molecular evolution. This book gives an account of such a new approach, through clear tutorial contributions by leading scientists specializing in the different fields involved.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700 1 _aPorto, Markus.
_eeditor.
_9330066
700 1 _aRoman, H. Eduardo.
_eeditor.
_9330067
700 1 _aVendruscolo, Michele.
_eeditor.
_9330068
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9783540353058
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-3-540-35306-5
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c295555
_d295555