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001			296533
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008			150903s2007 gw | o |||| 0|eng d
020			_a9783540489825 _99783540489825
024	7		_a10.1007/9783540489825 _2doi
035			_avtls000349784
039		9	_a201509030456 _bVLOAD _c201405050347 _dVLOAD _y201402071211 _zstaff
040			_aMX-SnUAN _bspa _cMX-SnUAN _erda
050		4	_aRM1-950
100	1		_aBourne, H. _eeditor. _9331682
245	1	0	_aGPCRs: From Deorphanization to Lead Structure Identification / _cedited by H. Bourne, R. Horuk, J. Kuhnke, H. Michel.
264		1	_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg, _c2007.
300			_axvii, 267 páginas 59 ilustraciones _brecurso en línea.
336			_atexto _btxt _2rdacontent
337			_acomputadora _bc _2rdamedia
338			_arecurso en línea _bcr _2rdacarrier
347			_aarchivo de texto _bPDF _2rda
490	0		_aErnst Schering Foundation Symposium Proceedings, _x0947-6075 ; _v2006/2
500			_aSpringer eBooks
505	0		_aG-Proteins and GPCRs: From the Beginning -- Modeling GPCRs -- QSAR Modeling of GPCR Ligands: Methodologies and Examples of Applications -- Privileged Structures in GPCRs -- Designing Compound Libraries Targeting GPCRs -- Orphan Seven Transmembrane Receptor Screening -- The Role of GPCR Dimerisation/Oligomerisation in Receptor Signalling -- Deorphanization of G-Protein-Coupled Receptors -- Virus-Encoded G-Protein-Coupled Receptors: Constitutively Active (Dys)Regulators of Cell Function and Their Potential as Drug Target -- Modulation of GPCR Conformationsby Ligands, G-Proteins, and Arrestins -- High Content Screening to Monitor G Protein-Coupled Receptor Internalisation -- High-Throughput Lead Finding and Optimisation for GPCR Targets.
520			_aBased on the international workshop GPCRs: From Deorphanisation to Lead Structure Identification, held in Berlin in May 2006, the book highlights the following topics: Structure of GPCRs, Design of GPCR Ligands, GPCR Signalling, Deorphanization and Assay Development. All chapters are written by leading experts in the field, discussing the most recent state of the art. They give insight into the approaches taken by industry and academia to address GPCRs and depict how mature this target class-oriented research has become in the last decade. The book reflects the actual trends in the fast-emerging field of GPCR research in academia and industry.
590			_aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700	1		_aHoruk, R. _eeditor. _9331683
700	1		_aKuhnke, J. _eeditor. _9331684
700	1		_aMichel, H. _eeditor. _9331685
710	2		_aSpringerLink (Servicio en línea) _9299170
776	0	8	_iEdición impresa: _z9783540489818
856	4	0	_uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-3-540-48982-5 _zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
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999			_c296533 _d296533