000 03289nam a22003855i 4500
001 296535
003 MX-SnUAN
005 20160429155326.0
007 cr nn 008mamaa
008 150903s2007 gw | o |||| 0|eng d
020 _a9783540495482
_99783540495482
024 7 _a10.1007/9783540495482
_2doi
035 _avtls000349833
039 9 _a201509030454
_bVLOAD
_c201405050348
_dVLOAD
_y201402071212
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aRC648-665.2
100 1 _aKorach, K. S.
_eeditor.
_9331686
245 1 0 _aTissue-Specific Estrogen Action :
_bNovel Mechanisms, Novel Ligands, Novel Therapies /
_cedited by K. S. Korach, T. Wintermantel.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2007.
300 _axv, 181 páginas 42 ilustraciones
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aErnst Schering Foundation Symposium Proceedings,
_x0947-6075 ;
_v2006/1
500 _aSpringer eBooks
505 0 _aInterfering with the Dynamics of Estrogen Receptor-Regulated Transcription -- Actions of Estrogen and Estrogen Receptors in Nonclassical Target Tissues -- Genetic Dissection of Estrogen Receptor Signaling In Vivo -- Of Mice and Men: The Many Guises of Estrogens -- Estradiol Action in Atherosclerosis and Reendothelialization -- Functional Effects and Molecular Mechanisms of Subtype-Selective ER? and ER? Agonists in the Cardiovascular System -- Pathogenesis and Therapy of Rheumatoid Arthritis -- The Role of ER? and ER? in theProstate: Insights from Genetic Models and Isoform-Selective Ligands -- Preclinical Characterization of Selective Estrogen Receptor ? Agonists: New Insights into Their Therapeutic Potential -- Exploiting Nongenomic Estrogen Receptor-Mediated Signaling for the Development of Pathway-Selective Estrogen Receptor Ligands.
520 _aThe multiple actions of estrogens on different cell types have not only intrigued endocrinology researchers but also inspired the development of selective estrogen receptor modulators, or SERMs, that modulate estrogen signaling in a cell type-specific manner. Current molecular understanding of estrogen action has greatly profited from advances in molecular cell biology to dissect the mechanisms of estrogen-regulated gene expression in target cells, from in vivo analyses using genetic models deficient in estrogen signaling and from synthetic estrogen receptor ligands with isoform- or pathway-selective activity. These advances, and their implications for clinical use, were discussed by leading researchers from industry and academia during an international symposium held in Berlin, 1-3 March 2006.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700 1 _aWintermantel, T.
_eeditor.
_9331687
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9783540495475
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-3-540-49548-2
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c296535
_d296535