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008 150903s2008 gw | o |||| 0|eng d
020 _a9783540734932
_99783540734932
024 7 _a10.1007/9783540734932
_2doi
035 _avtls000350598
039 9 _a201509030419
_bVLOAD
_c201405060237
_dVLOAD
_y201402171101
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aRG133.5
100 1 _aConneely, O.
_eeditor.
_9332845
245 1 0 _aProgestins and the Mammary Gland :
_bFrom Basic Science to Clinical Applications /
_cedited by O. Conneely, C. Otto.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2008.
300 _brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aErnst Schering Foundation Symposium Proceedings,
_x0947-6075 ;
_v2007/1
500 _aSpringer eBooks
505 0 _aDynamic Regulation of Progesterone Receptor Activity in Female Reproductive Tissues -- Steroid Receptor Coactivator 2: An Essential Coregulator of Progestin-Induced Uterine and Mammary Morphogenesis -- Inhibition of Mammary Tumorigenesis by Estrogen and Progesterone in Genetically Engineered Mice -- Estrogens, Progestins, and Risk of Breast Cancer -- Mammary Development, Carcinomas and Progesterone: Role of Wnt Signalling -- Progesterone Signaling in Mammary Gland Development -- Progesterone Receptor Isoforms in Normal and Malignant Breast -- In Vivo Characterization of Progestins with Reduced Non-genomic Activity In Vitro -- In Vitro and In Vivo Characterization of a Novel Nonsteroidal, Species-Specific Progesterone Receptor Modulator, PRA-910.
520 _aProgestins play a key role in reproductive endocrinology and as pharmaceutical drugs for contraception and in combined hormone therapy. To further our understanding of progestin action in the mammary gland, an international symposium, attended by leading researchers from academia and industry, was held in Berlin, 21–23 March 2007. Genetic mouse models helped to elucidate the role of progestins, both in normal breast development and in disease. Mechanistic molecular studies inspired the design of new progestins with improved tissue selectivity. In addition, the clinical impact of progesterone receptor agonists and antagonists for the prevention and treatment of breast cancer was discussed.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700 1 _aOtto, C.
_eeditor.
_9332846
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9783540734925
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-3-540-73493-2
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
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