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001			297663
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008			150903s2008 gw | o |||| 0|eng d
020			_a9783540755692 _99783540755692
024	7		_a10.1007/9783540755692 _2doi
035			_avtls000351117
039		9	_a201509030503 _bVLOAD _c201405060245 _dVLOAD _y201402171113 _zstaff
040			_aMX-SnUAN _bspa _cMX-SnUAN _erda
050		4	_aQH345
100	1		_aPosas, Francesc. _eeditor. _9333543
245	1	0	_aStress-Activated Protein Kinases / _cedited by Francesc Posas, Angel R. Nebreda.
264		1	_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg, _c2008.
300			_axviii, 312 páginas _brecurso en línea.
336			_atexto _btxt _2rdacontent
337			_acomputadora _bc _2rdamedia
338			_arecurso en línea _bcr _2rdacarrier
347			_aarchivo de texto _bPDF _2rda
490	0		_aTopics in Current Genetics, _x1610-2096 ; _v20
500			_aSpringer eBooks
505	0		_aMAPK Kinase Kinase Regulation of SAPK/JNK Pathways -- Alternative p38 MAPK Pathways -- The regulation of stress-activated MAP kinase signalling by protein phosphatases -- Transcriptional regulation by the p38 MAPK signaling pathway in mammalian cells -- Regulation of gene expression in response to osmostress by the yeast stress-activated protein kinase Hog1 -- Regulation of Tumorigenesis by p38? MAP Kinase -- Control of Cell Cycle by SAPKs in Budding and Fission Yeast -- Hog1-mediated Metabolic Adjustments Following Hyperosmotic Shock in the Yeast Saccharomyces cerevisiae -- Control of mRNA Stability by SAPKs -- Intrinsically Active (MKK-Independent) Variants of SAPKs – How do They Work? -- Regulation of MAPK Signaling in Yeast -- Modeling the Dynamics of Stress Activated Protein Kinases (SAPK) in Cellular Stress Response -- Stress-activated Protein Kinase Signaling in Drosophila -- Protein Kinases as Substrates for SAPKs -- Functions of stress-activated MAP kinases in the immune response -- Stress-activated MAP Kinases in Chromatin and Transcriptional Complexes -- SAPK and Translational Control.
520			_aTo maximize the probability of survival, cells need to coordinate their intracellular activities in response to changes in the extracellular environment. MAP kinase cascades play an important role in the transduction of signals inside eukaryotic cells. In particular, stress stimuli result in the rapid activation of a highly conserved group of MAP kinases, known as SAPKs (Stress-Activated Protein Kinases). These kinases coordinate the generation of adaptive responses that are essential for cell survival, which include the modulation of several aspects of cell physiology from metabolism to gene expression. In this book, leading researchers in the field discuss the state-of-the-art of many aspects of SAPK signalling in various systems from yeast to mammals. These include various chapters on regulatory mechanisms as well as the contribution of the SAPK signalling pathways to processes such as gene expression, metabolism, cell cycle regulation, immune responses and tumorigenesis.
590			_aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700	1		_aNebreda, Angel R. _eeditor. _9333544
710	2		_aSpringerLink (Servicio en línea) _9299170
776	0	8	_iEdición impresa: _z9783540755685
856	4	0	_uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-3-540-75569-2 _zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
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999			_c297663 _d297663